Reactome Pathway Database
Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Reactome Pathway Database
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Schema
>
EntityWithAccessionedSequence
>
Entries
p-6Y-FLT3 R595_L601dup [plasma membrane]
Show undefined attributes
Go to Details
compartment
[Compartment:876] plasma membrane
componentOf
[Complex:R-HSA-9696095] p-6Y-FLT3 R595_L601dup dimer [plasma membrane] - Homo sapiens
[Complex:R-HSA-9696095] p-6Y-FLT3 R595_L601dup dimer [plasma membrane] - Homo sapiens
created
[InstanceEdit:9696040] Rothfels, Karen, 2020年07月17日
crossReference
[DatabaseIdentifier:11944921] Mondo:0018874
[DatabaseIdentifier:11944892] Mondo:0004992
[DatabaseIdentifier:9832470] COSMIC:COSV54045432
dbId
9696035
deleted
[Deleted:9832475] Deletion of instance: 9696049
disease
[Disease:1500689] cancer
[Disease:9630839] acute myeloid leukemia
displayName
p-6Y-FLT3 R595_L601dup [plasma membrane]
endCoordinate
993
hasModifiedResidue
[ModifiedResidue:9604760] O4'-phospho-L-tyrosine at 589
[ModifiedResidue:9604750] O4'-phospho-L-tyrosine at 591
[ModifiedResidue:9604772] O4'-phospho-L-tyrosine at 599
[ModifiedResidue:9604762] O4'-phospho-L-tyrosine at 768
[ModifiedResidue:9604765] O4'-phospho-L-tyrosine at 955
[ModifiedResidue:9604743] O4'-phospho-L-tyrosine at 969
[FragmentInsertionModification:9696029] Insertion of residues 595 to 601 at 602 from UniProt:P36888 FLT3
inDisease
true
literatureReference
[LiteratureReference:9649423] Flt3 mutations from patients with acute myeloid leukemia induce transformation of 32D cells mediated by the Ras and STAT5 pathways
[LiteratureReference:9696007] FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model
maxDepth
1
modified
[InstanceEdit:9832472] Orlic-Milacic, Marija, 2023年04月01日
name
p-6Y-FLT3 R595_L601dup
ITD3
W51
referenceEntity
[ReferenceGeneProduct:uniprot:P36888] UniProt:P36888 FLT3
referenceType
ReferenceGeneProduct
schemaClass
EntityWithAccessionedSequence
species
[Species:48887] Homo sapiens
stId
R-HSA-9696035
startCoordinate
27
updateTrackers
[UpdateTracker:9905911] Update Tracker - [EntityWithAccessionedSequence:9696035] p-6Y-FLT3 R595_L601dup [plasma membrane] - v85:[addLiteratureReference, modifyName]
Referrals
(updatedInstance)
[UpdateTracker:9905911] Update Tracker - [EntityWithAccessionedSequence:9696035] p-6Y-FLT3 R595_L601dup [plasma membrane] - v85:[addLiteratureReference, modifyName]
(replacementInstances)
[Deleted:9832475] Deletion of instance: 9696049
(hasComponent)
[Complex:R-HSA-9696095] p-6Y-FLT3 R595_L601dup dimer [plasma membrane]
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
Download
Close
AltStyle
によって変換されたページ
(->オリジナル)
/
アドレス:
モード:
デフォルト
音声ブラウザ
ルビ付き
配色反転
文字拡大
モバイル