Reactome Pathway Database

Schema > EntityWithAccessionedSequence > Entries

FLT3 F590_F605dup [plasma membrane] Show undefined attributes

compartment

[Compartment:876] plasma membrane

componentOf

[Complex:R-HSA-9691976] FLT3 F590_F605dup dimer [plasma membrane] - Homo sapiens
[Complex:R-HSA-9691976] FLT3 F590_F605dup dimer [plasma membrane] - Homo sapiens

created [InstanceEdit:9690085] Rothfels, Karen, 2020年05月25日

crossReference

dbId 9690084

disease

displayName FLT3 F590_F605dup [plasma membrane]

endCoordinate 993

hasModifiedResidue

[FragmentInsertionModification:9690087] Insertion of residues 590 to 605 at 606 from UniProt:P36888 FLT3

inDisease true

literatureReference

[LiteratureReference:9683350] Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product

maxDepth 1

memberOf

[CandidateSet:R-HSA-9691152] juxtamembrane domain mutants of FLT3 [plasma membrane] - Homo sapiens

modified [InstanceEdit:9831177] Orlic-Milacic, Marija, 2023年03月20日

name

FLT3 F590_F605dup
STK-1
Mt4

referenceEntity [ReferenceGeneProduct:uniprot:P36888] UniProt:P36888 FLT3

referenceType ReferenceGeneProduct

schemaClass EntityWithAccessionedSequence

species [Species:48887] Homo sapiens

stId R-HSA-9690084

startCoordinate 27

updateTrackers

[UpdateTracker:9905683] Update Tracker - [EntityWithAccessionedSequence:9690084] FLT3 F590_F605dup [plasma membrane] - v85:[modifyName]

Referrals

(updatedInstance)

[UpdateTracker:9905683] Update Tracker - [EntityWithAccessionedSequence:9690084] FLT3 F590_F605dup [plasma membrane] - v85:[modifyName]

(hasMember)

[CandidateSet:R-HSA-9691152] juxtamembrane domain mutants of FLT3 [plasma membrane]

(hasComponent)

[Complex:R-HSA-9691976] FLT3 F590_F605dup dimer [plasma membrane]

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