Reactome Pathway Database

Schema > EntityWithAccessionedSequence > Entries

FLT3 D600_L601insMGMGGECNPGRQ [plasma membrane] Show undefined attributes

compartment

[Compartment:876] plasma membrane

componentOf

[Complex:R-HSA-9691982] FLT3 D600_L601insMGMGGECNPGRQ dimer [plasma membrane] - Homo sapiens
[Complex:R-HSA-9691982] FLT3 D600_L601insMGMGGECNPGRQ dimer [plasma membrane] - Homo sapiens

created [InstanceEdit:9690085] Rothfels, Karen, 2020年05月25日

crossReference

dbId 9690076

disease

displayName FLT3 D600_L601insMGMGGECNPGRQ [plasma membrane]

endCoordinate 993

hasModifiedResidue

[FragmentReplacedModification:9690081] Replacement of residues 600 to 601 by DMGMGGECNPGRQL

inDisease true

literatureReference

[LiteratureReference:9683350] Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product

maxDepth 1

memberOf

[CandidateSet:R-HSA-9691152] juxtamembrane domain mutants of FLT3 [plasma membrane] - Homo sapiens

name

FLT3 D600_L601insMGMGGECNPGRQ
STK-1
Mt6

referenceEntity [ReferenceGeneProduct:uniprot:P36888] UniProt:P36888 FLT3

referenceType ReferenceGeneProduct

schemaClass EntityWithAccessionedSequence

species [Species:48887] Homo sapiens

stId R-HSA-9690076

startCoordinate 27

Referrals

(hasMember)

[CandidateSet:R-HSA-9691152] juxtamembrane domain mutants of FLT3 [plasma membrane]

(hasComponent)

[Complex:R-HSA-9691982] FLT3 D600_L601insMGMGGECNPGRQ dimer [plasma membrane]

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