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Search ...
Go!
Schema
>
EntityWithAccessionedSequence
>
Entries
p-6Y FLT3 D835N [plasma membrane]
Show undefined attributes
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compartment
[Compartment:876] plasma membrane
componentOf
[Complex:R-HSA-9682397] p-6Y FLT3 D835N dimer [plasma membrane] - Homo sapiens
[Complex:R-HSA-9682397] p-6Y FLT3 D835N dimer [plasma membrane] - Homo sapiens
created
[InstanceEdit:9682381] Rothfels, Karen, 2020年04月08日
crossReference
[DatabaseIdentifier:11944921] Mondo:0018874
[DatabaseIdentifier:11944892] Mondo:0004992
[DatabaseIdentifier:9682319] COSMIC:COSV54045151
dbId
9682378
disease
[Disease:1500689] cancer
[Disease:9630839] acute myeloid leukemia
displayName
p-6Y FLT3 D835N [plasma membrane]
endCoordinate
993
hasModifiedResidue
[ReplacedResidue:9682320] L-aspartic acid 835 replaced with L-asparagine
[ModifiedResidue:9604760] O4'-phospho-L-tyrosine at 589
[ModifiedResidue:9604750] O4'-phospho-L-tyrosine at 591
[ModifiedResidue:9604772] O4'-phospho-L-tyrosine at 599
[ModifiedResidue:9604762] O4'-phospho-L-tyrosine at 768
[ModifiedResidue:9604765] O4'-phospho-L-tyrosine at 955
[ModifiedResidue:9604743] O4'-phospho-L-tyrosine at 969
inDisease
true
literatureReference
[LiteratureReference:9682272] Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies
maxDepth
1
name
p-6Y FLT3 D835N
STK-1
referenceEntity
[ReferenceGeneProduct:uniprot:P36888] UniProt:P36888 FLT3
referenceType
ReferenceGeneProduct
schemaClass
EntityWithAccessionedSequence
species
[Species:48887] Homo sapiens
stId
R-HSA-9682378
startCoordinate
27
Referrals
(hasComponent)
[Complex:R-HSA-9682397] p-6Y FLT3 D835N dimer [plasma membrane]
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