Reactome Pathway Database

Schema > EntityWithAccessionedSequence > Entries

KIT W557_K558del [plasma membrane] Show undefined attributes

compartment

[Compartment:876] plasma membrane

componentOf

created [InstanceEdit:9670342] Rothfels, Karen, 2019年12月09日

crossReference

dbId 9670343

disease

displayName KIT W557_K558del [plasma membrane]

endCoordinate 976

hasModifiedResidue

[FragmentDeletionModification:9670333] Deletion of residues 557 to 558

inDisease true

literatureReference

[LiteratureReference:9670319] Ponatinib inhibits polyclonal drug-resistant KIT oncoproteins and shows therapeutic potential in heavily pretreated gastrointestinal stromal tumor (GIST) patients
[LiteratureReference:9669094] Complementary activity of tyrosine kinase inhibitors against secondary kit mutations in imatinib-resistant gastrointestinal stromal tumours

maxDepth 1

memberOf

name

KIT W557_K558del
Mast/stem cell growth factor receptor precursor
KIT_HUMAN
c-KIT

referenceEntity [ReferenceGeneProduct:uniprot:P10721] UniProt:P10721 KIT

referenceType ReferenceGeneProduct

schemaClass EntityWithAccessionedSequence

species [Species:48887] Homo sapiens

stId R-HSA-9670343

startCoordinate 26

Referrals

(hasMember)

(hasComponent)

[Complex:R-HSA-9670346] KIT W557_K558del dimer [plasma membrane]

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