Reactome Pathway Database

Schema > Complex > Entries

Phosphorylated heterodimers of ERBB2 KD mutants:p-Y349,Y350-SHC1 [plasma membrane] Show undefined attributes

compartment

[Compartment:876] plasma membrane

componentOf

[Complex:R-HSA-9664981] Phosphorylated heterodimers of ERBB2 KD mutants:p-Y349,Y350-SHC1:GRB2:SOS1 [plasma membrane] - Homo sapiens

consumedByEvent

[Reaction:R-HSA-9664983] Phosphorylated heterodimers of ERBB2 KD mutants recruit GRB2:SOS1 through SHC1 - Homo sapiens

created [InstanceEdit:9664972] Orlic-Milacic, Marija, 2019年10月28日

crossReference

[DatabaseIdentifier:11944892] Mondo:0004992

dbId 9664975

disease

[Disease:1500689] cancer

displayName Phosphorylated heterodimers of ERBB2 KD mutants:p-Y349,Y350-SHC1 [plasma membrane]

hasComponent

inDisease true

includedLocation

[Compartment:70101] cytosol

isChimeric false

maxDepth 8

name

Phosphorylated heterodimers of ERBB2 KD mutants:p-Y349,Y350-SHC1

producedByEvent

[Reaction:R-HSA-9664976] Phosphorylated heterodimers of ERBB2 KD mutants phosphorylate SHC1 - Homo sapiens

schemaClass Complex

species

[Species:48887] Homo sapiens

stId R-HSA-9664975

updateTrackers

[UpdateTracker:9905292] Update Tracker - [Complex:9664975] Phosphorylated heterodimers of ERBB2 KD mutants:p-Y349,Y350-SHC1 [plasma membrane] - v85:[updateContainedComponent]

Referrals

(updatedInstance)

[UpdateTracker:9905292] Update Tracker - [Complex:9664975] Phosphorylated heterodimers of ERBB2 KD mutants:p-Y349,Y350-SHC1 [plasma membrane] - v85:[updateContainedComponent]

(hasComponent)

[Complex:R-HSA-9664981] Phosphorylated heterodimers of ERBB2 KD mutants:p-Y349,Y350-SHC1:GRB2:SOS1 [plasma membrane]

(input)

[Reaction:R-HSA-9664983] Phosphorylated heterodimers of ERBB2 KD mutants recruit GRB2:SOS1 through SHC1

(diseaseEntity)

[EntityFunctionalStatus:9664980] gain_of_function of Phosphorylated heterodimers of ERBB2 KD mutants:p-Y349,Y350-SHC1 [plasma membrane]

(output)

[Reaction:R-HSA-9664976] Phosphorylated heterodimers of ERBB2 KD mutants phosphorylate SHC1

© 2025 Reactome

Cite Us!