Reactome Pathway Database
Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Reactome Pathway Database
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Schema
>
FailedReaction
>
Entries
Defective OGG1 mutants show decreased binding to 8-oxoguanine
Show undefined attributes
Go to Details
authored
[InstanceEdit:9656251] Orlic-Milacic, Marija, 2019年07月30日
category
transition
compartment
[Compartment:7660] nucleoplasm
created
[InstanceEdit:9656251] Orlic-Milacic, Marija, 2019年07月30日
crossReference
[DatabaseIdentifier:11944904] Mondo:0004975
[DatabaseIdentifier:11944892] Mondo:0004992
dbId
9656254
disease
[Disease:1500689] cancer
[Disease:8863054] Alzheimer's disease
displayName
Defective OGG1 mutants show decreased binding to 8-oxoguanine
edited
[InstanceEdit:9663704] Orlic-Milacic, Marija, 2019年10月10日
entityFunctionalStatus
[EntityFunctionalStatus:9656305] loss_of_function of OGG1 mutants (8oxoG binding) [nucleoplasm]
eventOf
[Pathway:R-HSA-9656255] Defective OGG1 Substrate Binding - Homo sapiens
input
[GenomeEncodedEntity:R-HSA-110184] (8oxoG:Cyt)-dsDNA [nucleoplasm]
[DefinedSet:R-HSA-9656269] OGG1 mutants (8oxoG binding) [nucleoplasm]
isChimeric
false
isInDisease
true
isInferred
false
literatureReference
[LiteratureReference:9656282] Identification and characterization of OGG1 mutations in patients with Alzheimer's disease
maxDepth
1
modified
[InstanceEdit:9830342] Matthews, Lisa, 2023年03月08日
name
Defective OGG1 mutants show decreased binding to 8-oxoguanine
normalReaction
[Reaction:R-HSA-110235] OGG1 glycosylase mediated recognition and binding of an 8-oxoguanine opposite to a cytosine
releaseDate
2019年12月10日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:9663702] Vlahopoulos, Spiros, 2019年10月02日
[InstanceEdit:9663703] Boldogh, Istvan, 2019年10月08日
schemaClass
FailedReaction
species
[Species:48887] Homo sapiens
stId
R-HSA-9656254
summation
[Summation:9656304] OGG1 missense mutants reported in Alzheimer's disease, OGG1 ...
Referrals
(hasEvent)
[Pathway:R-HSA-9656255] Defective OGG1 Substrate Binding
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
Download
Close
AltStyle
によって変換されたページ
(->オリジナル)
/
アドレス:
モード:
デフォルト
音声ブラウザ
ルビ付き
配色反転
文字拡大
モバイル