Reactome Pathway Database

Schema > EntityWithAccessionedSequence > Entries

p-S621-RAF1 P261T [cytosol] Show undefined attributes

compartment

[Compartment:70101] cytosol

created [InstanceEdit:9656116] Rothfels, Karen, 2019年07月27日

crossReference

dbId 9656115

disease

displayName p-S621-RAF1 P261T [cytosol]

endCoordinate 648

hasModifiedResidue

inDisease true

literatureReference

[LiteratureReference:9655515] Molecular and clinical analysis of RAF1 in Noonan syndrome and related disorders: dephosphorylation of serine 259 as the essential mechanism for mutant activation
[LiteratureReference:9655523] Spectrum of mutations in Noonan syndrome and their correlation with phenotypes

maxDepth 1

memberOf

[CandidateSet:R-HSA-9656159] p-S621 RAF1 CR2 mutants [cytosol] - Homo sapiens

name

p-S621-RAF1 P261T
RAF proto-oncogene serine/threonine-protein kinase
Raf-1
C-RAF
cRaf

referenceEntity [ReferenceGeneProduct:uniprot:P04049] UniProt:P04049 RAF1

referenceType ReferenceGeneProduct

schemaClass EntityWithAccessionedSequence

species [Species:48887] Homo sapiens

stId R-HSA-9656115

startCoordinate 1

Referrals

(hasMember)

[CandidateSet:R-HSA-9656159] p-S621 RAF1 CR2 mutants [cytosol]

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