Reactome Pathway Database

Schema > EntityWithAccessionedSequence > Entries

p-S338,Y341,T492,S494,S621 RAF1 T260I [cytosol] Show undefined attributes

candidateOf

[CandidateSet:R-HSA-9656152] activated RAF1 CR2 mutants [cytosol] - Homo sapiens

compartment

[Compartment:70101] cytosol

created [InstanceEdit:9656073] Rothfels, Karen, 2019年07月27日

crossReference

dbId 9656074

disease

[Disease:6788675] hypertrophic cardiomyopathy

displayName p-S338,Y341,T492,S494,S621 RAF1 T260I [cytosol]

endCoordinate 648

hasModifiedResidue

inDisease true

literatureReference

[LiteratureReference:444324] Gain-of-function RAF1 mutations cause Noonan and LEOPARD syndromes with hypertrophic cardiomyopathy

maxDepth 1

modified [InstanceEdit:9656084] Rothfels, Karen, 2019年07月27日

name

p-S338,Y341,T492,S494,S621 RAF1 T260I
RAF proto-oncogene serine/threonine-protein kinase
Raf-1
C-RAF
cRaf

referenceEntity [ReferenceGeneProduct:uniprot:P04049] UniProt:P04049 RAF1

referenceType ReferenceGeneProduct

schemaClass EntityWithAccessionedSequence

species [Species:48887] Homo sapiens

stId R-HSA-9656074

startCoordinate 1

Referrals

(hasCandidate)

[CandidateSet:R-HSA-9656152] activated RAF1 CR2 mutants [cytosol]

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