Reactome Pathway Database

Schema > Reaction > Entries

PPE2 binds KPNA1:KPNB1 Show undefined attributes

authored

[InstanceEdit:9635702] Stephan, Ralf, 2019年02月06日

category binding

compartment

[Compartment:70101] cytosol

created [InstanceEdit:9636267] Koile, Daniel, 2019年02月12日

crossReference

[DatabaseIdentifier:11944914] Mondo:0018076

dbId 9636251

disease

[Disease:1660556] tuberculosis

displayName PPE2 binds KPNA1:KPNB1

edited

[InstanceEdit:9636267] Koile, Daniel, 2019年02月12日

eventOf

[Pathway:R-HSA-9636249] Inhibition of nitric oxide production - Homo sapiens

followingEvent

[BlackBoxEvent:R-HSA-9636247] PPE2:KPNA1:KPNB1 translocates to the nucleus - Homo sapiens

input

isChimeric false

isInDisease true

isInferred false

literatureReference

[LiteratureReference:9636246] The PPE2 protein of Mycobacterium tuberculosis translocates to host nucleus and inhibits nitric oxide production

maxDepth 1

modified [InstanceEdit:9830342] Matthews, Lisa, 2023年03月08日

name

PPE2 binds KPNA1:KPNB1

output

[Complex:R-HSA-9636269] PPE2:KPNA1:KPNB1 [cytosol]

relatedSpecies

[Species:176806] Mycobacterium tuberculosis

releaseDate 2019年12月10日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:9664478] Deffur, Armin, Wilkinson, RJ, 2019年10月23日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-9636251

summation

[Summation:9636260] PPE family protein PPE2 is transported via the importin-?/? ...

Referrals

(hasEvent)

[Pathway:R-HSA-9636249] Inhibition of nitric oxide production

(precedingEvent)

[BlackBoxEvent:R-HSA-9636247] PPE2:KPNA1:KPNB1 translocates to the nucleus

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