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GPER1 signaling Show undefined attributes

authored

[InstanceEdit:9632125] Rothfels, Karen, 2018年12月14日

created [InstanceEdit:9634596] Rothfels, Karen, 2019年01月11日

dbId 9634597

displayName GPER1 signaling

edited

[InstanceEdit:9758183] Rothfels, Karen, 2021年11月09日

eventOf

[Pathway:R-HSA-418555] G alpha (s) signalling events - Homo sapiens

hasDiagram true

hasEHLD false

hasEvent

[Reaction:R-HSA-9036307] GPER:Heterotrimeric G-protein Gs binds ESTG - Homo sapiens
[Reaction:R-HSA-9036301] ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s - Homo sapiens
[Reaction:R-HSA-9036308] ESTG-stimulated dissociation of GPER:heterotrimeric G-protein (s) complex - Homo sapiens
[Reaction:R-HSA-163617] G alpha (s) activates adenylate cyclase - Homo sapiens
[BlackBoxEvent:R-HSA-9624014] SHC1 is phosphorylated downstream of estrogen stimulation of GPER1 - Homo sapiens
[Reaction:R-HSA-9624017] p-SHC1 binds integrin alpha5beta1:fibronectin - Homo sapiens
[Reaction:R-HSA-392129] Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate - Homo sapiens
[Reaction:R-HSA-8951727] cAMP binds PKA tetramer - Homo sapiens
[Reaction:R-HSA-111925] cAMP induces dissociation of inactive PKA tetramers - Homo sapiens
[Reaction:R-HSA-111924] PKA catalytic subunit translocates to the nucleus - Homo sapiens

isInDisease false

isInferred false

literatureReference

maxDepth 2

modified [InstanceEdit:11033291] Weiser, Joel, 2025年08月28日

name

GPER1 signaling

orthologousEvent

previousReviewStatus [ReviewStatus:9821384] two stars

releaseDate 2021年12月08日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

schemaClass Pathway

species

[Species:48887] Homo sapiens

stId R-HSA-9634597

summation

[Summation:9634660] GPER1 (also known as GPR30) is an orphan G-protein coupled r...

updateTrackers

[UpdateTracker:9864354] Update Tracker - [Pathway:9634597] GPER1 signaling - v88:[updateContainedRLE]

Referrals

(updatedInstance)

[UpdateTracker:9864354] Update Tracker - [Pathway:9634597] GPER1 signaling - v88:[updateContainedRLE]

(hasEvent)

[Pathway:R-HSA-418555] G alpha (s) signalling events

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