Reactome Pathway Database

Schema > Reaction > Entries

FOXO1,FOXO3,FOXO4 bind p-2S-SMAD2/3:SMAD4 Show undefined attributes

authored

[InstanceEdit:9624371] Orlic-Milacic, Marija, 2018年10月11日

category binding

compartment

[Compartment:7660] nucleoplasm

created [InstanceEdit:9617992] Orlic-Milacic, Marija, 2018年08月31日

dbId 9617996

displayName FOXO1,FOXO3,FOXO4 bind p-2S-SMAD2/3:SMAD4

edited

[InstanceEdit:9627016] Orlic-Milacic, Marija, 2018年10月31日

eventOf

[Pathway:R-HSA-9617828] FOXO-mediated transcription of cell cycle genes - Homo sapiens

followingEvent

input

isChimeric false

isInDisease false

isInferred false

literatureReference

[LiteratureReference:9617983] Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation

maxDepth 1

modified [InstanceEdit:10867632] Weiser, Joel, 2025年08月27日

name

FOXO1,FOXO3,FOXO4 bind p-2S-SMAD2/3:SMAD4

orthologousEvent

output

[Complex:R-HSA-9617984] FOXO1,FOXO3,FOXO4:p-2S-SMAD2/3:SMAD4 [nucleoplasm]

precedingEvent

[BlackBoxEvent:R-HSA-173488] The SMAD2/3:SMAD4 complex transfers to the nucleus - Homo sapiens

releaseDate 2018年12月13日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-9617996

summation

[Summation:9617980] In response to TGF-beta signaling, forkhead box transcriptio...

Referrals

(hasEvent)

[Pathway:R-HSA-9617828] FOXO-mediated transcription of cell cycle genes

(precedingEvent)

© 2025 Reactome

Cite Us!