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TXN disrupts FOXO4 complex with EP300 Show undefined attributes

authored

[InstanceEdit:9624371] Orlic-Milacic, Marija, 2018年10月11日

catalystActivity

[CatalystActivity:9617734] thioredoxin-disulfide reductase (NADPH) activity of TXN [nucleoplasm]

category transition

compartment

[Compartment:7660] nucleoplasm

created [InstanceEdit:9617736] Orlic-Milacic, Marija, 2018年08月30日

dbId 9617735

displayName TXN disrupts FOXO4 complex with EP300

edited

[InstanceEdit:9627016] Orlic-Milacic, Marija, 2018年10月31日

eventOf

[Pathway:R-HSA-9617629] Regulation of FOXO transcriptional activity by acetylation - Homo sapiens

inferredFrom

[Reaction:R-NUL-9617742] TXN disrupts Foxo4 comples with EP300 - Homo sapiens

input

isChimeric false

isInDisease false

isInferred true

maxDepth 1

modified [InstanceEdit:9830342] Matthews, Lisa, 2023年03月08日

name

TXN disrupts FOXO4 complex with EP300

output

precedingEvent

[Reaction:R-HSA-9617683] EP300,CREBBP bind SOH-C481-FOXO4 - Homo sapiens

regulatedBy

[NegativeRegulation:9617749] Negative regulation by 'TXNIP [nucleoplasm]'

releaseDate 2018年12月13日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-9617735

summation

[Summation:9617741] Thioredoxin (TXN) reduces oxidized FOXO4 and disrupts intera...

Referrals

(hasEvent)

[Pathway:R-HSA-9617629] Regulation of FOXO transcriptional activity by acetylation

(inferredTo)

[Reaction:R-NUL-9617742] TXN disrupts Foxo4 comples with EP300

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