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Entries
MECR dimer reduces tdec2-CoA to DEC-CoA
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authored
[InstanceEdit:8952867] Jassal, Bijay, 2016年12月20日
catalystActivity
[CatalystActivity:8952869] trans-2-enoyl-CoA reductase (NADPH) activity of MECR dimer [mitochondrial matrix]
category
transition
compartment
[Compartment:5460] mitochondrial matrix
created
[InstanceEdit:8952867] Jassal, Bijay, 2016年12月20日
crossReference
[DatabaseIdentifier:12610784] Rhea:44961
dbId
8952873
displayName
MECR dimer reduces tdec2-CoA to DEC-CoA
edited
[InstanceEdit:8952867] Jassal, Bijay, 2016年12月20日
eventOf
[Pathway:R-HSA-77346] Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA - Homo sapiens
input
[SimpleEntity:R-ALL-113529] H+ [mitochondrial matrix]
[SimpleEntity:R-ALL-113600] NADPH [mitochondrial matrix]
[SimpleEntity:R-ALL-77343] tdec2-CoA [mitochondrial matrix]
isChimeric
false
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:8952871] Structural enzymological studies of 2-enoyl thioester reductase of the human mitochondrial FAS II pathway: new insights into its substrate recognition properties
[LiteratureReference:8952868] Characterization of 2-enoyl thioester reductase from mammals. An ortholog of YBR026p/MRF1'p of the yeast mitochondrial fatty acid synthesis type II
maxDepth
1
modified
[InstanceEdit:11033291] Weiser, Joel, 2025年08月28日
name
MECR dimer reduces tdec2-CoA to DEC-CoA
orthologousEvent
[Reaction:R-SCE-8952873] MECR dimer reduces tdec2-CoA to DEC-CoA - Saccharomyces cerevisiae
[Reaction:R-SPO-8952873] MECR dimer reduces tdec2-CoA to DEC-CoA - Schizosaccharomyces pombe
[Reaction:R-DDI-8952873] MECR dimer reduces tdec2-CoA to DEC-CoA - Dictyostelium discoideum
[Reaction:R-CEL-8952873] MECR dimer reduces tdec2-CoA to DEC-CoA - Caenorhabditis elegans
[Reaction:R-DME-8952873] MECR dimer reduces tdec2-CoA to DEC-CoA - Drosophila melanogaster
[Reaction:R-GGA-8952873] MECR dimer reduces tdec2-CoA to DEC-CoA - Gallus gallus
[Reaction:R-XTR-8952873] MECR dimer reduces tdec2-CoA to DEC-CoA - Xenopus tropicalis
[Reaction:R-DRE-8952873] MECR dimer reduces tdec2-CoA to DEC-CoA - Danio rerio
[Reaction:R-SSC-8952873] MECR dimer reduces tdec2-CoA to DEC-CoA - Sus scrofa
[Reaction:R-BTA-8952873] MECR dimer reduces tdec2-CoA to DEC-CoA - Bos taurus
[Reaction:R-CFA-8952873] MECR dimer reduces tdec2-CoA to DEC-CoA - Canis familiaris
[Reaction:R-RNO-8952873] MECR dimer reduces tdec2-CoA to DEC-CoA - Rattus norvegicus
[Reaction:R-MMU-8952873] MECR dimer reduces tdec2-CoA to DEC-CoA - Mus musculus
output
[SimpleEntity:R-ALL-77308] DEC-CoA [mitochondrial matrix]
[SimpleEntity:R-ALL-113563] NADP+ [mitochondrial matrix]
precedingEvent
[Reaction:R-HSA-109998] Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA - Homo sapiens
releaseDate
2017年03月27日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:8954302] D'Eustachio, Peter, 2017年01月06日
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-8952873
summation
[Summation:8952861] Mitochondrial trans-2-enoyl-CoA reductase (MECR aka NBRF1) i...
Referrals
(hasEvent)
[Pathway:R-HSA-77346] Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA
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