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Schema
>
Complex
>
Entries
RUNX2:CBFB [nucleoplasm]
Show undefined attributes
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candidateOf
[CandidateSet:R-HSA-9008443] (p-S451-RUNX2:CBFB,RUNX2:CBFB,RUNX2:HDAC6) [nucleoplasm] - Homo sapiens
compartment
[Compartment:7660] nucleoplasm
componentOf
[Complex:R-HSA-8938367] RUNX2:CBFB:LGALS3 gene [nucleoplasm] - Homo sapiens
[Complex:R-HSA-8937863] RUNX2:CBFB:p-Y-YAP1 [nucleoplasm] - Homo sapiens
consumedByEvent
[Reaction:R-HSA-8938371] RUNX2:CBFB binds the LGALS3 gene promoter - Homo sapiens
[Reaction:R-HSA-8939670] RUNX2:CBFB binds the ITGA5 gene promoter - Homo sapiens
[Reaction:R-HSA-8939963] Activated AKT phosphorylates RUNX2 - Homo sapiens
[Reaction:R-HSA-8939833] RUNX2:CBFB binds the ITGBL1 gene promoter - Homo sapiens
[Reaction:R-HSA-9009451] RUNX2 binds SMURF1 gene - Homo sapiens
[Reaction:R-HSA-9009282] CDK1 phosphorylates RUNX2 - Homo sapiens
[Reaction:R-HSA-9008832] RUNX2 binds BAX gene promoter - Homo sapiens
[Reaction:R-HSA-8878257] RUNX2 binds the IHH gene promoter - Homo sapiens
[Reaction:R-HSA-8939852] RUNX2 and SP7 bind the UCMA gene promoter - Homo sapiens
[Reaction:R-HSA-9009208] Activated ERKs phosphorylate RUNX2 - Homo sapiens
[Reaction:R-HSA-8937864] RUNX2 binds tyrosine phosphorylated YAP1 - Homo sapiens
[Reaction:R-HSA-9008412] CDK4 phosphorylates RUNX2 - Homo sapiens
[Reaction:R-HSA-8877941] RUNX2 binds SMAD1 in the nucleus - Homo sapiens
created
[InstanceEdit:8865412] Orlic-Milacic, Marija, 2016年03月22日
dbId
8865420
displayName
RUNX2:CBFB [nucleoplasm]
hasComponent
[EntityWithAccessionedSequence:R-HSA-8865293] CBFB [nucleoplasm]
[CandidateSet:R-HSA-9007751] RUNX2 [nucleoplasm]
inDisease
false
inferredTo
[Complex:R-MMU-8865420] RUNX2:CBFB [nucleoplasm] - Mus musculus
[Complex:R-RNO-8865420] RUNX2:CBFB [nucleoplasm] - Rattus norvegicus
[Complex:R-CFA-8865420] RUNX2:CBFB [nucleoplasm] - Canis familiaris
[Complex:R-BTA-8865420] RUNX2:CBFB [nucleoplasm] - Bos taurus
[Complex:R-SSC-8865420] RUNX2:CBFB [nucleoplasm] - Sus scrofa
[Complex:R-GGA-8865420] RUNX2:CBFB [nucleoplasm] - Gallus gallus
[Complex:R-DME-8865420] RUNX2:CBFB [nucleoplasm] - Drosophila melanogaster
[Complex:R-CEL-8865420] RUNX2:CBFB [nucleoplasm] - Caenorhabditis elegans
isChimeric
false
literatureReference
[LiteratureReference:8865398] Cbfbeta interacts with Runx2 and has a critical role in bone development
maxDepth
3
memberOf
[CandidateSet:R-HSA-9008881] RUNX2:CBFB,p-S451-RUNX2:CBFB,(p-2S-RUNX2:CBFB) [nucleoplasm] - Homo sapiens
modified
[InstanceEdit:9007753] Orlic-Milacic, Marija, 2017年06月02日
name
RUNX2:CBFB
producedByEvent
[Reaction:R-HSA-9008822] PPM1D dephosphorylates RUNX2 - Homo sapiens
[Reaction:R-HSA-8865425] RUNX2 binds CBFB - Homo sapiens
schemaClass
Complex
species
[Species:48887] Homo sapiens
stId
R-HSA-8865420
updateTrackers
[UpdateTracker:9897741] Update Tracker - [Complex:8865420] RUNX2:CBFB [nucleoplasm] - v62:[add_removeHasComponent]
Referrals
(updatedInstance)
[UpdateTracker:9897741] Update Tracker - [Complex:8865420] RUNX2:CBFB [nucleoplasm] - v62:[add_removeHasComponent]
(input)
[Reaction:R-HSA-8938371] RUNX2:CBFB binds the LGALS3 gene promoter
[Reaction:R-HSA-8939670] RUNX2:CBFB binds the ITGA5 gene promoter
[Reaction:R-HSA-8939963] Activated AKT phosphorylates RUNX2
[Reaction:R-HSA-8939833] RUNX2:CBFB binds the ITGBL1 gene promoter
[Reaction:R-HSA-9009451] RUNX2 binds SMURF1 gene
[Reaction:R-HSA-9009282] CDK1 phosphorylates RUNX2
[Reaction:R-HSA-9008832] RUNX2 binds BAX gene promoter
[Reaction:R-HSA-8878257] RUNX2 binds the IHH gene promoter
[Reaction:R-HSA-8939852] RUNX2 and SP7 bind the UCMA gene promoter
[Reaction:R-HSA-9009208] Activated ERKs phosphorylate RUNX2
[Reaction:R-HSA-8937864] RUNX2 binds tyrosine phosphorylated YAP1
[Reaction:R-HSA-8877941] RUNX2 binds SMAD1 in the nucleus
[Reaction:R-HSA-9008412] CDK4 phosphorylates RUNX2
(hasComponent)
[Complex:R-HSA-8938367] RUNX2:CBFB:LGALS3 gene [nucleoplasm]
[Complex:R-HSA-8939664] RUNX2:CBFB:ITGA5 gene [nucleoplasm]
[Complex:R-HSA-8939834] RUNX2:CBFB:ITGBL1 gene [nucleoplasm]
[Complex:R-HSA-9009447] RUNX2:CBFB:SMURF1 gene [nucleoplasm]
[Complex:R-HSA-9008858] RUNX2:CBFB:BAX gene [nucleoplasm]
[Complex:R-HSA-8878255] RUNX2:CBFB:IHH gene [nucleoplasm]
[Complex:R-HSA-8939856] RUNX2:CBFB:SP7:UCMA gene [nucleoplasm]
[Complex:R-HSA-8937863] RUNX2:CBFB:p-Y-YAP1 [nucleoplasm]
[Complex:R-HSA-8877936] RUNX2:CBFB:p-2S-SMAD1:p-2S-SMAD1:SMAD4 [nucleoplasm]
(activeUnit)
[PositiveGeneExpressionRegulation:R-HSA-8938383] Positive gene expression regulation by 'RUNX2:CBFB:LGALS3 gene [nucleoplasm]'
[PositiveGeneExpressionRegulation:R-HSA-9009255] Positive gene expression regulation by 'RUNX2:CBFB:ITGBL1 gene [nucleoplasm]'
[PositiveGeneExpressionRegulation:R-HSA-8939661] Positive gene expression regulation by 'RUNX2:CBFB:ITGA5 gene [nucleoplasm]'
[PositiveGeneExpressionRegulation:R-HSA-9009454] Positive gene expression regulation by 'RUNX2:CBFB:SMURF1 gene [nucleoplasm]'
[PositiveGeneExpressionRegulation:R-HSA-9008864] Positive gene expression regulation by 'RUNX2:CBFB:BAX gene [nucleoplasm]'
[PositiveGeneExpressionRegulation:R-HSA-8939869] Positive gene expression regulation by 'RUNX2:CBFB:SP7:UCMA gene [nucleoplasm]'
(output)
[Reaction:R-HSA-9008822] PPM1D dephosphorylates RUNX2
[Reaction:R-HSA-8865425] RUNX2 binds CBFB
(hasMember)
[CandidateSet:R-HSA-9008881] RUNX2:CBFB,p-S451-RUNX2:CBFB,(p-2S-RUNX2:CBFB) [nucleoplasm]
(hasCandidate)
[CandidateSet:R-HSA-9008443] (p-S451-RUNX2:CBFB,RUNX2:CBFB,RUNX2:HDAC6) [nucleoplasm]
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