Reactome Pathway Database

Schema > Reaction > Entries

FLT3LG dimer:FLT3 binds FLT3 Show undefined attributes

authored

[InstanceEdit:5578882] Jupe, Steve, 2014年06月04日

category binding

compartment

created [InstanceEdit:8854731] Jupe, Steve, 2016年01月28日

dbId 8854736

displayName FLT3LG dimer:FLT3 binds FLT3

edited

[InstanceEdit:8854731] Jupe, Steve, 2016年01月28日

eventOf

[Pathway:R-HSA-9607240] FLT3 Signaling - Homo sapiens

followingEvent

[BlackBoxEvent:R-HSA-9604767] FLT3LG dimer:FLT3 dimer autophosphorylates - Homo sapiens

input

isChimeric false

isInDisease false

isInferred false

literatureReference

[LiteratureReference:8854715] Structural insights into the extracellular assembly of the hematopoietic Flt3 signaling complex

maxDepth 1

modified [InstanceEdit:10424722] Weiser, Joel, 2025年08月27日

name

FLT3LG dimer:FLT3 binds FLT3

orthologousEvent

output

[Complex:R-HSA-8854716] FLT3LG dimer:FLT3 dimer [plasma membrane]

precedingEvent

[Reaction:R-HSA-6786789] FLT3LG dimer binds FLT3 - Homo sapiens

releaseDate 2016年03月23日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:8854753] Meldal, Birgit, 2016年01月28日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-8854736

summation

[Summation:8854743] Binding of FLT3LG to monomeric FLT3 induces receptor dimeriz...

Referrals

(hasEvent)

[Pathway:R-HSA-9607240] FLT3 Signaling

(precedingEvent)

[BlackBoxEvent:R-HSA-9604767] FLT3LG dimer:FLT3 dimer autophosphorylates

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