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Schema
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Entries
Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2
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catalystActivity
[CatalystActivity:77317] acyl-CoA dehydrogenase activity of ACADS tetramer [mitochondrial matrix]
category
transition
compartment
[Compartment:5460] mitochondrial matrix
created
[InstanceEdit:77247] Gillespie, ME, 2003年09月19日 00:00:00
crossReference
[DatabaseIdentifier:12610684] Rhea:31208
dbId
77327
displayName
Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2
eventOf
[Pathway:R-HSA-77350] Beta oxidation of hexanoyl-CoA to butanoyl-CoA - Homo sapiens
followingEvent
[Reaction:R-HSA-77325] trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA - Homo sapiens
[Reaction:R-HSA-169260] Reducing equivalents from beta-oxidation of fatty acids transfer to ETF - Homo sapiens
input
[SimpleEntity:R-ALL-113596] FAD [mitochondrial matrix]
[SimpleEntity:R-ALL-77326] HX-CoA [mitochondrial matrix]
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:77398] On the mechanism of dehydrogenation of fatty acyl derivatives of coenzyme A. II. The electron-transferring flavoprotein.
[LiteratureReference:70739] Purification and properties of short chain acyl-CoA, medium chain acyl-CoA, and isovaleryl-CoA dehydrogenases from human liver
maxDepth
1
modified
[InstanceEdit:10778922] Weiser, Joel, 2025年08月27日
name
Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2
orthologousEvent
[Reaction:R-DME-77327] Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 - Drosophila melanogaster
[Reaction:R-GGA-77327] Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 - Gallus gallus
[Reaction:R-XTR-77327] Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 - Xenopus tropicalis
[Reaction:R-DRE-77327] Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 - Danio rerio
[Reaction:R-SSC-77327] Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 - Sus scrofa
[Reaction:R-BTA-77327] Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 - Bos taurus
[Reaction:R-CFA-77327] Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 - Canis familiaris
[Reaction:R-RNO-77327] Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 - Rattus norvegicus
[Reaction:R-MMU-77327] Hexanoyl-CoA+FAD<=>trans-Hex-2-enoyl-CoA+FADH2 - Mus musculus
output
[SimpleEntity:R-ALL-31649] FADH2 [mitochondrial matrix]
[SimpleEntity:R-ALL-77324] trans-Hex-2-enoyl-CoA [mitochondrial matrix]
precedingEvent
[Reaction:R-HSA-77329] 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA - Homo sapiens
releaseDate
2004年07月06日
reviewStatus
[ReviewStatus:9821382] five stars
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-77327
summation
[Summation:178861] At the beginning of this reaction, 1 molecule of 'Hexanoyl-C...
Referrals
(hasEvent)
[Pathway:R-HSA-77350] Beta oxidation of hexanoyl-CoA to butanoyl-CoA
(precedingEvent)
[Reaction:R-HSA-169260] Reducing equivalents from beta-oxidation of fatty acids transfer to ETF
[Reaction:R-HSA-77325] trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA
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