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Schema
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Reaction
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Entries
lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2
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catalystActivity
[CatalystActivity:77259] acyl-CoA dehydrogenase activity of ACADL tetramer [mitochondrial matrix]
category
transition
compartment
[Compartment:5460] mitochondrial matrix
created
[InstanceEdit:77247] Gillespie, ME, 2003年09月19日 00:00:00
crossReference
[DatabaseIdentifier:12610672] Rhea:31040
dbId
77263
displayName
lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2
eventOf
[Pathway:R-HSA-77310] Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA - Homo sapiens
followingEvent
[Reaction:R-HSA-77256] 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA - Homo sapiens
[Reaction:R-HSA-169260] Reducing equivalents from beta-oxidation of fatty acids transfer to ETF - Homo sapiens
input
[SimpleEntity:R-ALL-113596] FAD [mitochondrial matrix]
[SimpleEntity:R-ALL-77261] LAU-CoA [mitochondrial matrix]
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:77398] On the mechanism of dehydrogenation of fatty acyl derivatives of coenzyme A. II. The electron-transferring flavoprotein.
[LiteratureReference:77400] Beta-oxidation of long-chain fatty acids by human fibroblasts: evidence for a novel long-chain acyl-coenzyme A dehydrogenase.
maxDepth
1
modified
[InstanceEdit:10680101] Weiser, Joel, 2025年08月27日
name
lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2
orthologousEvent
[Reaction:R-GGA-77263] lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 - Gallus gallus
[Reaction:R-XTR-77263] lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 - Xenopus tropicalis
[Reaction:R-DRE-77263] lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 - Danio rerio
[Reaction:R-SSC-77263] lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 - Sus scrofa
[Reaction:R-BTA-77263] lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 - Bos taurus
[Reaction:R-CFA-77263] lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 - Canis familiaris
[Reaction:R-RNO-77263] lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 - Rattus norvegicus
[Reaction:R-MMU-77263] lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2 - Mus musculus
output
[SimpleEntity:R-ALL-77255] 2-trans-Dodecenoyl-CoA [mitochondrial matrix]
[SimpleEntity:R-ALL-31649] FADH2 [mitochondrial matrix]
precedingEvent
[Reaction:R-HSA-77271] 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA - Homo sapiens
releaseDate
2004年07月06日
reviewStatus
[ReviewStatus:9821382] five stars
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-77263
summation
[Summation:178928] At the beginning of this reaction, 1 molecule of 'Lauroyl-Co...
Referrals
(hasEvent)
[Pathway:R-HSA-77310] Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA
(precedingEvent)
[Reaction:R-HSA-169260] Reducing equivalents from beta-oxidation of fatty acids transfer to ETF
[Reaction:R-HSA-77256] 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA
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