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Schema
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Pathway
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Entries
Signal attenuation
Show undefined attributes
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authored
[InstanceEdit:74816] 2003年07月28日 10:05:14
compartment
[Compartment:70101] cytosol
created
[InstanceEdit:74963] Bevan, AP, 2003年07月31日 08:01:55
crossReference
[DatabaseIdentifier:12758014] BioModels Database:BIOMD0000000466
[DatabaseIdentifier:12758018] BioModels Database:BIOMD0000000468
[DatabaseIdentifier:12757982] BioModels Database:BIOMD0000000424
dbId
74749
displayName
Signal attenuation
eventOf
[Pathway:R-HSA-74751] Insulin receptor signalling cascade - Homo sapiens
hasDiagram
false
hasEHLD
false
hasEvent
[Reaction:R-HSA-74747] Dephosphorylation of p-Y-IRS1,p-Y-IRS2 - Homo sapiens
[BlackBoxEvent:R-HSA-74748] De-phosphorylation of p-Y427-SHC1 - Homo sapiens
[Reaction:R-HSA-109822] MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 - Homo sapiens
[Reaction:R-HSA-5686074] GRB2-1:p-4S-SOS1:p-Y427-SHC1 dissociates - Homo sapiens
[Reaction:R-HSA-109823] MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 - Homo sapiens
[Reaction:R-HSA-5686315] GRB2:p-4S-SOS1:p-Y-IRS1,p-Y-IRS2 dissociates - Homo sapiens
[Reaction:R-HSA-110011] Binding of Grb10 to the insulin receptor - Homo sapiens
isInDisease
false
isInferred
false
lastUpdatedDate
2020年03月16日
maxDepth
2
modified
[InstanceEdit:12757879] Weiser, Joel, 2025年08月05日
name
Signal attenuation
orthologousEvent
[Pathway:R-DRE-74749] Signal attenuation - Danio rerio
[Pathway:R-DME-74749] Signal attenuation - Drosophila melanogaster
[Pathway:R-GGA-74749] Signal attenuation - Gallus gallus
[Pathway:R-XTR-74749] Signal attenuation - Xenopus tropicalis
[Pathway:R-SSC-74749] Signal attenuation - Sus scrofa
[Pathway:R-BTA-74749] Signal attenuation - Bos taurus
[Pathway:R-CFA-74749] Signal attenuation - Canis familiaris
[Pathway:R-RNO-74749] Signal attenuation - Rattus norvegicus
[Pathway:R-MMU-74749] Signal attenuation - Mus musculus
releaseDate
2005年04月11日
reviewStatus
[ReviewStatus:9821382] five stars
schemaClass
Pathway
species
[Species:48887] Homo sapiens
stId
R-HSA-74749
summation
[Summation:74750] Now with the complete receptor-ligand dissociation and subse...
updateTrackers
[UpdateTracker:9781067] Update Tracker - [Pathway:74749] Signal attenuation - v61:[updateContainedRLE]
[UpdateTracker:9779850] Update Tracker - [Pathway:74749] Signal attenuation - v64:[updateContainedRLE]
[UpdateTracker:9779025] Update Tracker - [Pathway:74749] Signal attenuation - v66:[updateContainedRLE]
[UpdateTracker:9784668] Update Tracker - [Pathway:74749] Signal attenuation - v53:[add_removeHasEvent, updateContainedRLE]
[UpdateTracker:9777230] Update Tracker - [Pathway:74749] Signal attenuation - v72:[updateContainedRLE]
Referrals
(updatedInstance)
[UpdateTracker:9781067] Update Tracker - [Pathway:74749] Signal attenuation - v61:[updateContainedRLE]
[UpdateTracker:9779850] Update Tracker - [Pathway:74749] Signal attenuation - v64:[updateContainedRLE]
[UpdateTracker:9779025] Update Tracker - [Pathway:74749] Signal attenuation - v66:[updateContainedRLE]
[UpdateTracker:9784668] Update Tracker - [Pathway:74749] Signal attenuation - v53:[add_removeHasEvent, updateContainedRLE]
[UpdateTracker:9777230] Update Tracker - [Pathway:74749] Signal attenuation - v72:[updateContainedRLE]
(hasEvent)
[Pathway:R-HSA-74751] Insulin receptor signalling cascade
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