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Resynthesis of excised residue by POLB Show undefined attributes

authored

[InstanceEdit:110327] Matthews, L, 2004年01月29日 18:52:00

catalystActivity

[CatalystActivity:5649635] DNA-directed DNA polymerase activity of LIG3:XRCC1:POLB:SSB-gap-dsDNA [nucleoplasm]

category transition

compartment

[Compartment:7660] nucleoplasm

created [InstanceEdit:110175] Matthews, L, 2004年01月29日 08:00:00

dbId 73932

displayName Resynthesis of excised residue by POLB

edited

eventOf

[Pathway:R-HSA-110381] Resolution of AP sites via the single-nucleotide replacement pathway - Homo sapiens

followingEvent

[Reaction:R-HSA-73931] LIG3-mediated DNA ligation via the single-nucleotide replacement pathway - Homo sapiens

input

isInDisease false

isInferred false

literatureReference

[LiteratureReference:111257] Reconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein.

maxDepth 1

modified [InstanceEdit:10948619] Weiser, Joel, 2025年08月27日

name

Resynthesis of excised residue by POLB

orthologousEvent

output

precedingEvent

[Reaction:R-HSA-110376] Recruitment of LIG3:XRCC1 complex to the site of repair by POLB - Homo sapiens

releaseDate 2004年03月06日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:5673689] Borowiec, James, 2014年12月22日

revised

[InstanceEdit:5654671] Orlic-Milacic, Marija, 2014年12月03日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-73932

summation

[Summation:110378] POLB (DNA polymerase beta) mediates DNA synthesis that fills...

updateTrackers

Referrals

(updatedInstance)

(hasEvent)

[Pathway:R-HSA-110381] Resolution of AP sites via the single-nucleotide replacement pathway

(precedingEvent)

[Reaction:R-HSA-73931] LIG3-mediated DNA ligation via the single-nucleotide replacement pathway

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