beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA)

catalystActivity
catalystActivityReference [CatalystActivityReference:9643717] methylcrotonoyl-CoA carboxylase activity of 6x(Btn-MCCC1:MCCC2) [mitochondrial matrix] The molecular basis of human 3-methylcrotonyl-CoA carboxylase deficiency
category transition
compartment
crossReference
dbId 70773
displayName beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA)
eventOf
followingEvent
input
isInDisease false
isInferred false
literatureReference
maxDepth 1
modified [InstanceEdit:10948619] Weiser, Joel, 2025年08月27日
name
  • beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA)
  • 3-methyl-(2E)-butenoyl-CoA + ATP + hydrogencarbonate => 3-methyl-(2E)-glutaconyl-CoA + ADP + H(+) + phosphate
negativePrecedingEvent
orthologousEvent
output
precedingEvent
previousReviewStatus [ReviewStatus:9821385] four stars
releaseDate 2004年07月06日
reviewStatus [ReviewStatus:9821382] five stars
reviewed
schemaClass Reaction
species
stId R-HSA-70773
summation
updateTrackers
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