Reactome Pathway Database

TPI1 dimer isomerizes GA3P to DHAP Show undefined attributes

catalystActivity

[CatalystActivity:70453] triose-phosphate isomerase activity of TPI1 dimer [cytosol]

catalystActivityReference [CatalystActivityReference:9644044] triose-phosphate isomerase activity of TPI1 dimer [cytosol] Primary structure of human triosephosphate isomerase

category transition

compartment

[Compartment:70101] cytosol

crossReference

dbId 70481

displayName TPI1 dimer isomerizes GA3P to DHAP

eventOf

[Pathway:R-HSA-70263] Gluconeogenesis - Homo sapiens

followingEvent

[Reaction:R-HSA-71495] Aldolase tetramers convert GA3P and DHAP to F1,6PP - Homo sapiens

input

[SimpleEntity:R-ALL-29578] GA3P [cytosol]

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:11064438] Weiser, Joel, 2025年08月28日

name

TPI1 dimer isomerizes GA3P to DHAP
D-glyceraldehyde 3-phosphate => dihydroxyacetone phosphate

orthologousEvent

output

[SimpleEntity:R-ALL-75970] DHAP [cytosol]

precedingEvent

[Reaction:R-HSA-70482] GAPDH tetramers reduce 1,3BPG to GA3P - Homo sapiens

releaseDate 2004年07月06日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

revised

[InstanceEdit:9815860] D'Eustachio, Peter, 2022年08月29日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-70481

summation

[Summation:71448] The reversible conversion of GA3P (glyceraldehyde-3-phosphat...

updateTrackers

Referrals

(updatedInstance)

(hasEvent)

[Pathway:R-HSA-70263] Gluconeogenesis

(precedingEvent)

[Reaction:R-HSA-71495] Aldolase tetramers convert GA3P and DHAP to F1,6PP

(reverseReaction)

[Reaction:R-HSA-70454] TPI1 dimer isomerizes DHAP to GA3P

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