Reactome Pathway Database

Schema > Reaction > Entries

DNA polymerase alpha:primase binds at the origin Show undefined attributes

category binding

compartment

[Compartment:7660] nucleoplasm

created [InstanceEdit:68951] Davey, MJ, O'Donnell, M, 2003年06月05日 08:03:13

dbId 68914

displayName DNA polymerase alpha:primase binds at the origin

eventOf

[Pathway:R-HSA-68962] Activation of the pre-replicative complex - Homo sapiens

figure

[Figure:68915] /figures/2.4.3a.jpg

followingEvent

[Reaction:R-HSA-68913] The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin - Homo sapiens

input

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:11064438] Weiser, Joel, 2025年08月28日

name

DNA polymerase alpha:primase binds at the origin

orthologousEvent

output

[Complex:R-HSA-68510] DNA polymerase alpha:primase:DNA polymerase alpha:origin complex [nucleoplasm]

precedingEvent

regulatedBy

[PositiveRegulation:R-HSA-69385] Positive regulation by 'CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm]'

releaseDate 2004年07月06日

reviewStatus [ReviewStatus:9821382] five stars

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-68914

summation

[Summation:69386] DNA polymerase alpha:primase is comprised of four subunits, ...

Referrals

(hasEvent)

[Pathway:R-HSA-68962] Activation of the pre-replicative complex

(precedingEvent)

[Reaction:R-HSA-68913] The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin

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