Reactome Pathway Database

Schema > Complex > Entries

p-S15,S20-TP53 Tetramer:APAF1 Gene [nucleoplasm] Show undefined attributes

compartment

[Compartment:7660] nucleoplasm

created [InstanceEdit:6791353] Orlic-Milacic, Marija, 2015年08月20日

dbId 6791350

displayName p-S15,S20-TP53 Tetramer:APAF1 Gene [nucleoplasm]

hasComponent

inDisease false

isChimeric false

literatureReference

[LiteratureReference:6791355] APAF-1 is a transcriptional target of p53 in DNA damage-induced apoptosis

maxDepth 3

modified [InstanceEdit:6799249] Orlic-Milacic, Marija, 2015年09月22日

name

p-S15,S20-TP53 Tetramer:APAF1 Gene

positivelyRegulates

[PositiveGeneExpressionRegulation:R-HSA-6791346] Positive gene expression regulation by 'p-S15,S20-TP53 Tetramer:APAF1 Gene [nucleoplasm]'

producedByEvent

[Reaction:R-HSA-6791349] TP53 binds the APAF1 gene promoter - Homo sapiens

schemaClass Complex

species

[Species:48887] Homo sapiens

stId R-HSA-6791350

Referrals

(output)

[Reaction:R-HSA-6791349] TP53 binds the APAF1 gene promoter

(regulator)

[PositiveGeneExpressionRegulation:R-HSA-6791346] Positive gene expression regulation by 'p-S15,S20-TP53 Tetramer:APAF1 Gene [nucleoplasm]'

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