Reactome Pathway Database
Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Reactome Pathway Database
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Schema
>
Reaction
>
Entries
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER
Show undefined attributes
Go to Details
authored
[InstanceEdit:110275] Hoeijmakers, JH, 2004年01月29日 18:08:33
[InstanceEdit:6783704] Orlic-Milacic, Marija, 2015年06月16日
catalystActivity
[CatalystActivity:6782209] DNA-directed DNA polymerase activity of TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm]
category
transition
compartment
[Compartment:7660] nucleoplasm
created
[InstanceEdit:6782207] Orlic-Milacic, Marija, 2015年06月05日
dbId
6782208
deleted
[Deleted:6793246] Deletion of instance: 110305
[Deleted:6793249] Deletion of instance: 110306
displayName
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER
edited
[InstanceEdit:6783704] Orlic-Milacic, Marija, 2015年06月16日
eventOf
[Pathway:R-HSA-6782210] Gap-filling DNA repair synthesis and ligation in TC-NER - Homo sapiens
followingEvent
[Reaction:R-HSA-6782227] Ligation of newly synthesized repair patch to incised DNA in TC-NER - Homo sapiens
input
[SimpleEntity:R-ALL-30555] dNTP [nucleoplasm]
[Complex:R-HSA-6782222] TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm]
isChimeric
false
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:5690036] Coordination of dual incision and repair synthesis in human nucleotide excision repair
[LiteratureReference:5690482] Replication protein A safeguards genome integrity by controlling NER incision events
[LiteratureReference:5690489] Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells
[LiteratureReference:6782218] Efficient PCNA complex formation is dependent upon both transcription coupled repair and genome overall repair
maxDepth
1
modified
[InstanceEdit:11064438] Weiser, Joel, 2025年08月28日
name
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER
orthologousEvent
[Reaction:R-DME-6782208] Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER - Drosophila melanogaster
[Reaction:R-PFA-6782208] Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER - Plasmodium falciparum
[Reaction:R-SCE-6782208] Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER - Saccharomyces cerevisiae
[Reaction:R-SPO-6782208] Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER - Schizosaccharomyces pombe
[Reaction:R-DDI-6782208] Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER - Dictyostelium discoideum
[Reaction:R-CEL-6782208] Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER - Caenorhabditis elegans
[Reaction:R-GGA-6782208] Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER - Gallus gallus
[Reaction:R-XTR-6782208] Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER - Xenopus tropicalis
[Reaction:R-SSC-6782208] Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER - Sus scrofa
[Reaction:R-BTA-6782208] Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER - Bos taurus
[Reaction:R-CFA-6782208] Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER - Canis familiaris
[Reaction:R-RNO-6782208] Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER - Rattus norvegicus
[Reaction:R-MMU-6782208] Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER - Mus musculus
output
[SimpleEntity:R-ALL-113541] PPi [nucleoplasm]
[Complex:R-HSA-6782220] TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm]
precedingEvent
[Reaction:R-HSA-6782224] 3' incision by ERCC5 (XPG) in TC-NER - Homo sapiens
releaseDate
2004年03月06日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:6790576] Fousteri, Maria, 2015年08月03日
revised
[InstanceEdit:6783704] Orlic-Milacic, Marija, 2015年06月16日
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-6782208
summation
[Summation:6782215] In transcription-coupled nucleotide excision repair (TC-NER)...
Referrals
(replacementInstances)
[Deleted:6793246] Deletion of instance: 110305
[Deleted:6793249] Deletion of instance: 110306
(hasEvent)
[Pathway:R-HSA-6782210] Gap-filling DNA repair synthesis and ligation in TC-NER
(precedingEvent)
[Reaction:R-HSA-6782227] Ligation of newly synthesized repair patch to incised DNA in TC-NER
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
Download
Close
AltStyle
によって変換されたページ
(->オリジナル)
/
アドレス:
モード:
デフォルト
音声ブラウザ
ルビ付き
配色反転
文字拡大
モバイル