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Go!
Schema
>
EntityWithAccessionedSequence
>
Entries
XPA [nucleoplasm]
Show undefined attributes
Go to Details
compartment
[Compartment:7660] nucleoplasm
componentOf
[Complex:R-HSA-5689300] Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] - Homo sapiens
[Complex:R-HSA-6790517] Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] - Homo sapiens
[Complex:R-HSA-6782111] TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] - Homo sapiens
[Complex:R-HSA-5690214] GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] - Homo sapiens
[Complex:R-HSA-6782205] TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] - Homo sapiens
[Complex:R-HSA-6782219] TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] - Homo sapiens
consumedByEvent
[Reaction:R-HSA-5689861] Recruitment of XPA and release of CAK - Homo sapiens
[Reaction:R-HSA-6782004] Assembly of the pre-incision complex in TC-NER - Homo sapiens
dbId
67437
displayName
XPA [nucleoplasm]
endCoordinate
273
inDisease
false
inferredTo
[EntityWithAccessionedSequence:R-MMU-67437] XPA [nucleoplasm] - Mus musculus
[EntityWithAccessionedSequence:R-RNO-67437] Xpa [nucleoplasm] - Rattus norvegicus
[EntityWithAccessionedSequence:R-CFA-67437] XPA [nucleoplasm] - Canis familiaris
[EntityWithAccessionedSequence:R-BTA-67437] XPA [nucleoplasm] - Bos taurus
[EntityWithAccessionedSequence:R-SSC-67437] XPA [nucleoplasm] - Sus scrofa
[EntityWithAccessionedSequence:R-DRE-67437] xpa [nucleoplasm] - Danio rerio
[EntityWithAccessionedSequence:R-XTR-67437] xpa [nucleoplasm] - Xenopus tropicalis
[EntityWithAccessionedSequence:R-GGA-67437] XPA [nucleoplasm] - Gallus gallus
[EntityWithAccessionedSequence:R-DME-67437] XPA [nucleoplasm] - Drosophila melanogaster
[EntityWithAccessionedSequence:R-CEL-67437] xpa-1 [nucleoplasm] - Caenorhabditis elegans
[GenomeEncodedEntity:R-DDI-67437] Ghost homologue of XPA [nucleoplasm] - Dictyostelium discoideum
[EntityWithAccessionedSequence:R-SPO-67437] XPA [nucleoplasm] - Schizosaccharomyces pombe
[EntityWithAccessionedSequence:R-SCE-67437] XPA [nucleoplasm] - Saccharomyces cerevisiae
[EntityWithAccessionedSequence:R-PFA-67437] XPA [nucleoplasm] - Plasmodium falciparum
maxDepth
1
modified
[InstanceEdit:4085262] Orlic-Milacic, M, 2013年08月02日
name
XPA
XPA protein
DNA-repair protein complementing XP-A cells (Xeroderma pigmentosum group A complementing protein)
xeroderma pigmentosum, complementation group A
DNA-repair protein complementing XP-A cells
Xeroderma pigmentosum group A complementing protein
producedByEvent
[Reaction:R-HSA-6782224] 3' incision by ERCC5 (XPG) in TC-NER - Homo sapiens
[Reaction:R-HSA-5690988] 3'-incision of DNA by ERCC5 (XPG) in GG-NER - Homo sapiens
referenceEntity
[ReferenceGeneProduct:uniprot:P23025] UniProt:P23025 XPA
referenceType
ReferenceGeneProduct
schemaClass
EntityWithAccessionedSequence
species
[Species:48887] Homo sapiens
stId
R-HSA-67437
startCoordinate
2
updateTrackers
[UpdateTracker:9874910] Update Tracker - [EntityWithAccessionedSequence:67437] XPA [nucleoplasm] - v44:[modifyEndCoordinate, modifyStartCoordinate]
[UpdateTracker:9888559] Update Tracker - [EntityWithAccessionedSequence:67437] XPA [nucleoplasm] - v46:[modifyName]
[UpdateTracker:9881130] Update Tracker - [EntityWithAccessionedSequence:67437] XPA [nucleoplasm] - v45:[addName]
Referrals
(updatedInstance)
[UpdateTracker:9874910] Update Tracker - [EntityWithAccessionedSequence:67437] XPA [nucleoplasm] - v44:[modifyEndCoordinate, modifyStartCoordinate]
[UpdateTracker:9888559] Update Tracker - [EntityWithAccessionedSequence:67437] XPA [nucleoplasm] - v46:[modifyName]
[UpdateTracker:9881130] Update Tracker - [EntityWithAccessionedSequence:67437] XPA [nucleoplasm] - v45:[addName]
(output)
[Reaction:R-HSA-6782224] 3' incision by ERCC5 (XPG) in TC-NER
[Reaction:R-HSA-5690988] 3'-incision of DNA by ERCC5 (XPG) in GG-NER
(hasComponent)
[Complex:R-HSA-6782219] TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm]
[Complex:R-HSA-6782205] TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm]
[Complex:R-HSA-6782111] TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm]
[Complex:R-HSA-9684117] TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm]
[Complex:R-HSA-6782066] TC-NER pre-incision complex [nucleoplasm]
[Complex:R-HSA-6782063] Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm]
[Complex:R-HSA-5689300] Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm]
[Complex:R-HSA-5691018] Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm]
[Complex:R-HSA-6790468] Ub,SUMO:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm]
[Complex:R-HSA-6790517] Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm]
[Complex:R-HSA-5691059] GG-NER incision complex:5'-incised damaged DNA [nucleoplasm]
[Complex:R-HSA-5690214] GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm]
(input)
[Reaction:R-HSA-6782004] Assembly of the pre-incision complex in TC-NER
[Reaction:R-HSA-5689861] Recruitment of XPA and release of CAK
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