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p-4Y-PLCG1 dissociates from activated FGFR3 point and translocation mutants Show undefined attributes

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authored

[InstanceEdit:2105031] Rothfels, K, 2012年02月09日

category dissociation

compartment

[Compartment:876] plasma membrane

created [InstanceEdit:5655319] Rothfels, Karen, 2014年12月05日

crossReference

dbId 5655247

deleted

[Deleted:5655671] Deletion of instance: 2077385

disease

displayName p-4Y-PLCG1 dissociates from activated FGFR3 point and translocation mutants

edited

[InstanceEdit:2252592] Rothfels, K, 2012年05月16日

entityFunctionalStatus

[EntityFunctionalStatus:5655338] gain_of_function of Activated FGFR3 point and translocation mutants:p-4Y-PLCG1 [plasma membrane]

eventOf

[Pathway:R-HSA-5655332] Signaling by FGFR3 in disease - Homo sapiens

input

[Complex:R-HSA-5655321] Activated FGFR3 point and translocation mutants:p-4Y-PLCG1 [plasma membrane]

isInDisease true

isInferred false

literatureReference

[LiteratureReference:189824] Phospholipase C-gamma as a signal-transducing element

maxDepth 1

modified [InstanceEdit:9830342] Matthews, Lisa, 2023年03月08日

name

p-4Y-PLCG1 dissociates from activated FGFR3 point and translocation mutants

normalReaction [Reaction:R-HSA-5654148] p-4Y-PLCG1 dissociates from activated FGFR3

output

precedingEvent

[Reaction:R-HSA-5655243] Activated FGFR3 point and translocation mutants phosphorylate PLCG1 - Homo sapiens

releaseDate 2012年06月12日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:2248845] Ezzat, S, 2012年05月15日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-5655247

summation

[Summation:191520] Dissociation from the activated receptor quickly follows pho...

Referrals

(replacementInstances)

[Deleted:5655671] Deletion of instance: 2077385

(hasEvent)

[Pathway:R-HSA-5655332] Signaling by FGFR3 in disease

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