Reactome Pathway Database

Schema > BlackBoxEvent > Entries

TP53 stimulates transcription of RRM2B gene Show undefined attributes

authored

[InstanceEdit:5659776] Orlic-Milacic, Marija, 2014年12月23日

category omitted

compartment

[Compartment:7660] nucleoplasm

created [InstanceEdit:5632891] Orlic-Milacic, Marija, 2014年10月29日

dbId 5632892

displayName TP53 stimulates transcription of RRM2B gene

edited

[InstanceEdit:5659776] Orlic-Milacic, Marija, 2014年12月23日

eventOf

[Pathway:R-HSA-5628897] TP53 Regulates Metabolic Genes - Homo sapiens

followingEvent

input

[EntityWithAccessionedSequence:R-HSA-5632883] RRM2B Gene [nucleoplasm]

isChimeric false

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:9830342] Matthews, Lisa, 2023年03月08日

name

TP53 stimulates transcription of RRM2B gene

output

[EntityWithAccessionedSequence:R-HSA-111792] RRM2B [cytosol]

precedingEvent

[Reaction:R-HSA-5632887] TP53 binds the RRM2B gene - Homo sapiens

regulatedBy

[PositiveGeneExpressionRegulation:R-HSA-5632893] Positive gene expression regulation by 'TP53 Tetramer:RRM2B Gene [nucleoplasm]'

regulationReference

[RegulationReference:9642131] Positive gene expression regulation by 'TP53 Tetramer:RRM2B Gene [nucleoplasm]' A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage

releaseDate 2015年03月19日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

schemaClass BlackBoxEvent

species

[Species:48887] Homo sapiens

stId R-HSA-5632892

summation

[Summation:5632900] TP53 (p53) directly stimulates transcription of RRM2B gene (...

updateTrackers

Referrals

(updatedInstance)

(hasEvent)

[Pathway:R-HSA-5628897] TP53 Regulates Metabolic Genes

(precedingEvent)

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