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Entries
Activation of the AP-1 family of transcription factors
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authored
[InstanceEdit:450323] Shamovsky, V, 2009年12月16日
compartment
[Compartment:7660] nucleoplasm
created
[InstanceEdit:450323] Shamovsky, V, 2009年12月16日
crossReference
[DatabaseIdentifier:12758020] BioModels Database:BIOMD0000000251
[DatabaseIdentifier:12757924] BioModels Database:BIOMD0000000504
[DatabaseIdentifier:12757928] BioModels Database:BIOMD0000000477
dbId
450341
displayName
Activation of the AP-1 family of transcription factors
edited
[InstanceEdit:532463] Shamovsky, V, 2010年02月27日
eventOf
[Pathway:R-HSA-450282] MAPK targets/ Nuclear events mediated by MAP kinases - Homo sapiens
hasDiagram
false
hasEHLD
false
hasEvent
[Reaction:R-HSA-168053] Phosphorylated MAPKs phosphorylate ATF-2 - Homo sapiens
[Reaction:R-HSA-168136] Activated JNKs phosphorylate c-JUN - Homo sapiens
[Reaction:R-HSA-450325] c-FOS activation by phospho ERK1/2 - Homo sapiens
[Reaction:R-HSA-168440] Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer. - Homo sapiens
[Reaction:R-HSA-450292] Formation of Activated Protein 1 (AP-1) complex. cFOS/c-JUN heterodimer. - Homo sapiens
isInDisease
false
isInferred
false
lastUpdatedDate
2016年12月21日
literatureReference
[LiteratureReference:500499] AP-1 function and regulation
[LiteratureReference:500501] The regulation of AP-1 activity by mitogen-activated protein kinases
[LiteratureReference:500505] AP-1 subunits: quarrel and harmony among siblings
maxDepth
2
modified
[InstanceEdit:12757879] Weiser, Joel, 2025年08月05日
name
Activation of the AP-1 family of transcription factors
orthologousEvent
[Pathway:R-SCE-450341] Activation of the AP-1 family of transcription factors - Saccharomyces cerevisiae
[Pathway:R-SPO-450341] Activation of the AP-1 family of transcription factors - Schizosaccharomyces pombe
[Pathway:R-CEL-450341] Activation of the AP-1 family of transcription factors - Caenorhabditis elegans
[Pathway:R-DME-450341] Activation of the AP-1 family of transcription factors - Drosophila melanogaster
[Pathway:R-GGA-450341] Activation of the AP-1 family of transcription factors - Gallus gallus
[Pathway:R-XTR-450341] Activation of the AP-1 family of transcription factors - Xenopus tropicalis
[Pathway:R-DRE-450341] Activation of the AP-1 family of transcription factors - Danio rerio
[Pathway:R-SSC-450341] Activation of the AP-1 family of transcription factors - Sus scrofa
[Pathway:R-BTA-450341] Activation of the AP-1 family of transcription factors - Bos taurus
[Pathway:R-CFA-450341] Activation of the AP-1 family of transcription factors - Canis familiaris
[Pathway:R-RNO-450341] Activation of the AP-1 family of transcription factors - Rattus norvegicus
[Pathway:R-MMU-450341] Activation of the AP-1 family of transcription factors - Mus musculus
releaseDate
2010年03月16日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:532466] Gillespie, ME, 2010年02月27日
schemaClass
Pathway
species
[Species:48887] Homo sapiens
stId
R-HSA-450341
summation
[Summation:500504] Activator protein-1 (AP-1) is a collective term referring to...
updateTrackers
[UpdateTracker:9782085] Update Tracker - [Pathway:450341] Activation of the AP-1 family of transcription factors - v59:[updateContainedRLE]
[UpdateTracker:9789745] Update Tracker - [Pathway:450341] Activation of the AP-1 family of transcription factors - v37:[updateContainedRLE]
Referrals
(updatedInstance)
[UpdateTracker:9782085] Update Tracker - [Pathway:450341] Activation of the AP-1 family of transcription factors - v59:[updateContainedRLE]
[UpdateTracker:9789745] Update Tracker - [Pathway:450341] Activation of the AP-1 family of transcription factors - v37:[updateContainedRLE]
(hasEvent)
[Pathway:R-HSA-450282] MAPK targets/ Nuclear events mediated by MAP kinases
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