Reactome Pathway Database
Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Reactome Pathway Database
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Schema
>
Pathway
>
Entries
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
Show undefined attributes
Go to Details
authored
[InstanceEdit:445353] Mahajan, SS, 2009年10月29日
compartment
[Compartment:876] plasma membrane
[Compartment:70101] cytosol
[Compartment:7660] nucleoplasm
created
[InstanceEdit:442716] Mahajan, SS, 2009年09月29日
crossReference
[DatabaseIdentifier:12758008] BioModels Database:BIOMD0000000427
[DatabaseIdentifier:12757960] BioModels Database:BIOMD0000000653
[DatabaseIdentifier:12757962] BioModels Database:BIOMD0000000656
[DatabaseIdentifier:12757970] BioModels Database:BIOMD0000000648
[DatabaseIdentifier:12757972] BioModels Database:BIOMD0000000655
[DatabaseIdentifier:12757976] BioModels Database:BIOMD0000000652
[DatabaseIdentifier:12757984] BioModels Database:BIOMD0000000654
dbId
442742
displayName
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
edited
[InstanceEdit:447013] Gillespie, ME, 2009年11月19日
[InstanceEdit:9628239] Orlic-Milacic, Marija, 2018年11月07日
eventOf
[Pathway:R-HSA-438064] Post NMDA receptor activation events - Homo sapiens
goBiologicalProcess
[GO_BiologicalProcess:645] chemical synaptic transmission
hasDiagram
false
hasEHLD
false
hasEvent
[Pathway:R-HSA-442982] Ras activation upon Ca2+ influx through NMDA receptor - Homo sapiens
[Pathway:R-HSA-444257] RSK activation - Homo sapiens
[Reaction:R-HSA-442724] Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) - Homo sapiens
isInDisease
false
isInferred
false
lastUpdatedDate
2023年03月29日
literatureReference
[LiteratureReference:444263] Genetics of childhood disorders: LII. Learning and memory, part 5: human cognitive disorders and the ras/ERK/CREB pathway
maxDepth
3
modified
[InstanceEdit:12757879] Weiser, Joel, 2025年08月05日
name
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
orthologousEvent
[Pathway:R-SCE-442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - Saccharomyces cerevisiae
[Pathway:R-SPO-442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - Schizosaccharomyces pombe
[Pathway:R-DDI-442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - Dictyostelium discoideum
[Pathway:R-CEL-442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - Caenorhabditis elegans
[Pathway:R-DME-442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - Drosophila melanogaster
[Pathway:R-GGA-442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - Gallus gallus
[Pathway:R-XTR-442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - Xenopus tropicalis
[Pathway:R-SSC-442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - Sus scrofa
[Pathway:R-BTA-442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - Bos taurus
[Pathway:R-CFA-442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - Canis familiaris
[Pathway:R-RNO-442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - Rattus norvegicus
[Pathway:R-MMU-442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - Mus musculus
releaseDate
2009年12月15日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:446792] Tukey, D, 2009年11月17日
[InstanceEdit:9627687] Yi, Feng, 2018年11月02日
[InstanceEdit:9628437] Hansen, Kasper B, 2018年11月02日
schemaClass
Pathway
species
[Species:48887] Homo sapiens
stId
R-HSA-442742
summation
[Summation:9620182] Ca2+ influx through the NMDA receptor activates RAS guanyl n...
updateTrackers
[UpdateTracker:9864142] Update Tracker - [Pathway:442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - v88:[updateContainedRLE]
[UpdateTracker:9790025] Update Tracker - [Pathway:442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - v35:[updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9778813] Update Tracker - [Pathway:442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - v67:[add_removeSummation, removeHasEvent, updateContainedPathway, updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9779714] Update Tracker - [Pathway:442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - v64:[updateContainedPathway]
[UpdateTracker:9780754] Update Tracker - [Pathway:442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - v62:[updateIndirectRLE]
[UpdateTracker:9846614] Update Tracker - [Pathway:442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - v84:[updateContainedRLE]
[UpdateTracker:9779019] Update Tracker - [Pathway:442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - v66:[updateIndirectRLE]
Referrals
(updatedInstance)
[UpdateTracker:9864142] Update Tracker - [Pathway:442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - v88:[updateContainedRLE]
[UpdateTracker:9790025] Update Tracker - [Pathway:442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - v35:[updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9778813] Update Tracker - [Pathway:442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - v67:[add_removeSummation, removeHasEvent, updateContainedPathway, updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9779714] Update Tracker - [Pathway:442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - v64:[updateContainedPathway]
[UpdateTracker:9780754] Update Tracker - [Pathway:442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - v62:[updateIndirectRLE]
[UpdateTracker:9846614] Update Tracker - [Pathway:442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - v84:[updateContainedRLE]
[UpdateTracker:9779019] Update Tracker - [Pathway:442742] CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling - v66:[updateIndirectRLE]
(hasEvent)
[Pathway:R-HSA-438064] Post NMDA receptor activation events
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
Download
Close
AltStyle
によって変換されたページ
(->オリジナル)
/
アドレス:
モード:
デフォルト
音声ブラウザ
ルビ付き
配色反転
文字拡大
モバイル