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Entries
Synthesis, secretion, and deacylation of Ghrelin
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authored
[InstanceEdit:426529] May, B, 2009年06月10日
compartment
[Compartment:7660] nucleoplasm
[Compartment:70101] cytosol
[Compartment:17957] endoplasmic reticulum lumen
[Compartment:12045] endoplasmic reticulum membrane
[Compartment:1462052] secretory granule lumen
[Compartment:984] extracellular region
created
[InstanceEdit:422063] May, B, 2009年05月25日 21:41:39
dbId
422085
deleted
[Deleted:2980740] Deletion of instance: 381150
displayName
Synthesis, secretion, and deacylation of Ghrelin
edited
[InstanceEdit:426529] May, B, 2009年06月10日
eventOf
[Pathway:R-HSA-2980736] Peptide hormone metabolism - Homo sapiens
goBiologicalProcess
[GO_BiologicalProcess:19561] peptide hormone processing
hasDiagram
true
hasEHLD
false
hasEvent
[BlackBoxEvent:R-HSA-422088] Expression of Preproghrelin - Homo sapiens
[Reaction:R-HSA-422051] Cleavage of the signal peptide of Preproghrelin - Homo sapiens
[Reaction:R-HSA-422104] Ghrelin O-acyltransferase octanoylates Proghrelin - Homo sapiens
[Reaction:R-HSA-422017] Ghrelin O-acyltransferase decanoylates Proghrelin - Homo sapiens
[Reaction:R-HSA-422021] PCSK1 hydrolyzes acyl Proghrelin to acyl Ghrelin - Homo sapiens
[BlackBoxEvent:R-HSA-422048] Acyl Ghrelin and C-Ghrelin are secreted - Homo sapiens
[Reaction:R-HSA-9023617] Butyrylcholinesterase hydrolyzes acyl Ghrelin - Homo sapiens
[Reaction:R-HSA-9023619] Platelet-activating factor acetylhydrolase (PLA2G7) hydrolyzes acyl Ghrelin - Homo sapiens
isInDisease
false
isInferred
false
lastUpdatedDate
2021年09月15日
literatureReference
[LiteratureReference:422105] Ghrelin fluctuation, what determines its production?
[LiteratureReference:422095] Ghrelin, des-acyl ghrelin and obestatin: three pieces of the same puzzle
maxDepth
2
modified
[InstanceEdit:10680101] Weiser, Joel, 2025年08月27日
name
Synthesis, secretion, and deacylation of Ghrelin
orthologousEvent
[Pathway:R-GGA-422085] Synthesis, secretion, and deacylation of Ghrelin - Gallus gallus
[Pathway:R-DRE-422085] Synthesis, secretion, and deacylation of Ghrelin - Danio rerio
[Pathway:R-SSC-422085] Synthesis, secretion, and deacylation of Ghrelin - Sus scrofa
[Pathway:R-BTA-422085] Synthesis, secretion, and deacylation of Ghrelin - Bos taurus
[Pathway:R-CFA-422085] Synthesis, secretion, and deacylation of Ghrelin - Canis familiaris
[Pathway:R-RNO-422085] Synthesis, secretion, and deacylation of Ghrelin - Rattus norvegicus
[Pathway:R-MMU-422085] Synthesis, secretion, and deacylation of Ghrelin - Mus musculus
releaseDate
2009年09月30日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:434405] Zhang, Weizhen, 2009年08月29日
schemaClass
Pathway
species
[Species:48887] Homo sapiens
stId
R-HSA-422085
summation
[Summation:422028] Ghrelin is a peptide hormone of 28 amino acid residues which...
updateTrackers
[UpdateTracker:9782823] Update Tracker - [Pathway:422085] Synthesis, secretion, and deacylation of Ghrelin - v58:[updateContainedRLE]
[UpdateTracker:9785304] Update Tracker - [Pathway:422085] Synthesis, secretion, and deacylation of Ghrelin - v52:[updateContainedRLE]
[UpdateTracker:9787625] Update Tracker - [Pathway:422085] Synthesis, secretion, and deacylation of Ghrelin - v44:[updateContainedRLE]
[UpdateTracker:9775686] Update Tracker - [Pathway:422085] Synthesis, secretion, and deacylation of Ghrelin - v78:[updateContainedRLE]
[UpdateTracker:9780426] Update Tracker - [Pathway:422085] Synthesis, secretion, and deacylation of Ghrelin - v63:[add_removeHasEvent]
[UpdateTracker:9788402] Update Tracker - [Pathway:422085] Synthesis, secretion, and deacylation of Ghrelin - v42:[updateContainedRLE]
[UpdateTracker:9790793] Update Tracker - [Pathway:422085] Synthesis, secretion, and deacylation of Ghrelin - v33:[updateContainedRLE]
Referrals
(updatedInstance)
[UpdateTracker:9782823] Update Tracker - [Pathway:422085] Synthesis, secretion, and deacylation of Ghrelin - v58:[updateContainedRLE]
[UpdateTracker:9785304] Update Tracker - [Pathway:422085] Synthesis, secretion, and deacylation of Ghrelin - v52:[updateContainedRLE]
[UpdateTracker:9787625] Update Tracker - [Pathway:422085] Synthesis, secretion, and deacylation of Ghrelin - v44:[updateContainedRLE]
[UpdateTracker:9775686] Update Tracker - [Pathway:422085] Synthesis, secretion, and deacylation of Ghrelin - v78:[updateContainedRLE]
[UpdateTracker:9780426] Update Tracker - [Pathway:422085] Synthesis, secretion, and deacylation of Ghrelin - v63:[add_removeHasEvent]
[UpdateTracker:9788402] Update Tracker - [Pathway:422085] Synthesis, secretion, and deacylation of Ghrelin - v42:[updateContainedRLE]
[UpdateTracker:9790793] Update Tracker - [Pathway:422085] Synthesis, secretion, and deacylation of Ghrelin - v33:[updateContainedRLE]
(replacementInstances)
[Deleted:2980740] Deletion of instance: 381150
(hasEvent)
[Pathway:R-HSA-2980736] Peptide hormone metabolism
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