Reactome | G alpha (i) auto-inactivates by hydrolysing GTP to GDP

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G alpha (i) auto-inactivates by hydrolysing GTP to GDP Show undefined attributes

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authored

[InstanceEdit:392218] Jupe, S, 2009年02月27日 15:59:25

catalystActivity

[CatalystActivity:392204] GTPase activity of G alpha (i): GTP [plasma membrane]

category transition

compartment

[Compartment:876] plasma membrane

created [InstanceEdit:392211] Jupe, S, 2009年02月27日 15:56:33

dbId 392212

displayName G alpha (i) auto-inactivates by hydrolysing GTP to GDP

edited

[InstanceEdit:435382] Jupe, S, 2009年09月09日

eventOf

[Pathway:R-HSA-418594] G alpha (i) signalling events - Homo sapiens

followingEvent

[Reaction:R-HSA-751001] Inactive G alpha (i) reassociates with G beta:gamma - Homo sapiens

inferredFrom

[Reaction:R-RNO-421896] G alpha (i)1 auto-inactivates by hydrolysing GTP to GDP - Rattus norvegicus

input

[Complex:R-HSA-392161] G alpha (i): GTP [plasma membrane]

isInDisease false

isInferred true

literatureReference

[LiteratureReference:374843] Mechanism of GTP hydrolysis by G-protein alpha subunits

maxDepth 1

modified [InstanceEdit:9830342] Matthews, Lisa, 2023年03月08日

name

G alpha (i) auto-inactivates by hydrolysing GTP to GDP

output

precedingEvent

regulatedBy

[PositiveRegulation:R-HSA-921125] Positive regulation by 'RGS proteins active for G alpha (i) [plasma membrane]'

regulationReference

[RegulationReference:9642661] Positive regulation by 'RGS proteins active for G alpha (i) [plasma membrane]' Cellular regulation of RGS proteins: modulators and integrators of G protein signaling

releaseDate 2009年09月30日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:425201] Akkerman, JW, 2009年06月03日

revised

[InstanceEdit:9012014] Varusai, Thawfeek, 2017年07月10日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-392212

summation

[Summation:400669] When a ligand activates a G protein-coupled receptor, it ind...

updateTrackers

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(updatedInstance)

(precedingEvent)

[Reaction:R-HSA-751001] Inactive G alpha (i) reassociates with G beta:gamma

(hasEvent)

[Pathway:R-HSA-418594] G alpha (i) signalling events

(inferredTo)

[Reaction:R-RNO-421896] G alpha (i)1 auto-inactivates by hydrolysing GTP to GDP

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Reactome Pathway Database

G alpha (i) auto-inactivates by hydrolysing GTP to GDP Show undefined attributes

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