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Schema
>
Reaction
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Entries
SOS binds Grb2 bound to pFAK:NCAM1
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authored
[InstanceEdit:391809] Garapati, P V, 2009年02月24日 10:31:15
category
binding
compartment
[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created
[InstanceEdit:392050] Garapati, P V, 2009年02月26日 17:43:29
dbId
392053
displayName
SOS binds Grb2 bound to pFAK:NCAM1
edited
[InstanceEdit:391881] Garapati, P V, 2009年02月24日 10:58:20
eventOf
[Pathway:R-HSA-375165] NCAM signaling for neurite out-growth - Homo sapiens
followingEvent
[Reaction:R-HSA-392054] NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras - Homo sapiens
[Reaction:R-HSA-5672965] RAS GEFs promote RAS nucleotide exchange - Homo sapiens
input
[Complex:R-HSA-392047] Grb2:pFAK bound to NCAM1:pFyn [plasma membrane]
[EntityWithAccessionedSequence:R-HSA-64847] SOS1 [cytosol]
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:391814] Cellular signalling mechanisms of neural cell adhesion molecules
[LiteratureReference:375028] Binding properties of the neural cell adhesion molecule to different components of the extracellular matrix
maxDepth
1
modified
[InstanceEdit:10867632] Weiser, Joel, 2025年08月27日
name
SOS binds Grb2 bound to pFAK:NCAM1
orthologousEvent
[Reaction:R-CEL-392053] SOS binds Grb2 bound to pFAK:NCAM1 - Caenorhabditis elegans
[Reaction:R-GGA-392053] SOS binds Grb2 bound to pFAK:NCAM1 - Gallus gallus
[Reaction:R-BTA-392053] SOS binds Grb2 bound to pFAK:NCAM1 - Bos taurus
[Reaction:R-CFA-392053] SOS binds Grb2 bound to pFAK:NCAM1 - Canis familiaris
[Reaction:R-RNO-392053] SOS binds Grb2 bound to pFAK:NCAM1 - Rattus norvegicus
[Reaction:R-MMU-392053] SOS binds Grb2 bound to pFAK:NCAM1 - Mus musculus
output
[Complex:R-HSA-392045] Grb2:Sos:pFAK bound to NCAM1:pFyn [plasma membrane]
precedingEvent
[Reaction:R-HSA-392051] Recruitment of Grb2 to pFAK:NCAM1 - Homo sapiens
releaseDate
2009年06月24日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:422107] Maness, PF, Walmod, PS, 2009年05月25日
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-392053
summation
[Summation:419866] Guanine nucleotide releasing factor Sos associates with FAK ...
updateTrackers
[UpdateTracker:9791117] Update Tracker - [Reaction:392053] SOS binds Grb2 bound to pFAK:NCAM1 - v32:[removeCatalystActivity]
Referrals
(updatedInstance)
[UpdateTracker:9791117] Update Tracker - [Reaction:392053] SOS binds Grb2 bound to pFAK:NCAM1 - v32:[removeCatalystActivity]
(precedingEvent)
[Reaction:R-HSA-392054] NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras
[Reaction:R-HSA-5672965] RAS GEFs promote RAS nucleotide exchange
(hasEvent)
[Pathway:R-HSA-375165] NCAM signaling for neurite out-growth
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