Reactome Pathway Database
Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Reactome Pathway Database
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Schema
>
Reaction
>
Entries
WNT-dependent phosphorylation of DVL
Show undefined attributes
Go to Details
authored
[InstanceEdit:3782517] Rothfels, K, 2013年06月28日
catalystActivity
[CatalystActivity:5250906] protein serine/threonine kinase activity of unknown kinase [cytosol]
category
transition
compartment
[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created
[InstanceEdit:3858488] Rothfels, K, 2013年07月09日
dbId
3858480
displayName
WNT-dependent phosphorylation of DVL
edited
[InstanceEdit:4663813] Matthews, L, 2013年10月07日
eventOf
[Pathway:R-HSA-4086400] PCP/CE pathway - Homo sapiens
followingEvent
[Reaction:R-HSA-3858475] ppDVL recruits RAC - Homo sapiens
[Reaction:R-HSA-3858489] ppDVL binds DAAM1 - Homo sapiens
inferredFrom
[Reaction:R-NUL-3858478] Rat Dvl is phosophorylated upon Wnt binding - Mus musculus
input
[SimpleEntity:R-ALL-113592] ATP [cytosol]
[Complex:R-HSA-3858484] WNT:FZD:pDVL [plasma membrane]
isChimeric
false
isInDisease
false
isInferred
true
literatureReference
[LiteratureReference:3858424] Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin
[LiteratureReference:3772339] Dishevelled: The hub of Wnt signaling
[LiteratureReference:5099861] Functional consequences of Wnt-induced dishevelled 2 phosphorylation in canonical and noncanonical Wnt signaling
maxDepth
1
modified
[InstanceEdit:9830342] Matthews, Lisa, 2023年03月08日
name
WNT-dependent phosphorylation of DVL
output
[SimpleEntity:R-ALL-29370] ADP [cytosol]
[CandidateSet:R-HSA-3858467] pp-DVL [cytosol]
[Complex:R-HSA-3858486] WNT:FZD [plasma membrane]
precedingEvent
[Reaction:R-HSA-3858482] DVL is recruited to the receptor - Homo sapiens
releaseDate
2013年12月04日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:5099870] Kikuchi, Akira, 2013年11月12日
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-3858480
summation
[Summation:3858438] In response to WNT signaling, dishevelled (DVL) proteins are...
updateTrackers
[UpdateTracker:9786822] Update Tracker - [Reaction:3858480] WNT-dependent phosphorylation of DVL - v48:[add_removeCatalystActivity]
[UpdateTracker:9777152] Update Tracker - [Reaction:3858480] WNT-dependent phosphorylation of DVL - v72:[modifyText]
Referrals
(updatedInstance)
[UpdateTracker:9786822] Update Tracker - [Reaction:3858480] WNT-dependent phosphorylation of DVL - v48:[add_removeCatalystActivity]
[UpdateTracker:9777152] Update Tracker - [Reaction:3858480] WNT-dependent phosphorylation of DVL - v72:[modifyText]
(precedingEvent)
[Reaction:R-HSA-3858475] ppDVL recruits RAC
[Reaction:R-HSA-3858489] ppDVL binds DAAM1
[NegativePrecedingEvent:9864365] Futile Cycle: WNT-dependent phosphorylation of DVL
(hasEvent)
[Pathway:R-HSA-4086400] PCP/CE pathway
(inferredTo)
[Reaction:R-NUL-3858478] Rat Dvl is phosophorylated upon Wnt binding
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
Download
Close
AltStyle
によって変換されたページ
(->オリジナル)
/
アドレス:
モード:
デフォルト
音声ブラウザ
ルビ付き
配色反転
文字拡大
モバイル