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Schema
>
DefinedSet
>
Entries
Ligand:GPCR complexes that activate Gi [plasma membrane]
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compartment
[Compartment:876] plasma membrane
componentOf
[Complex:R-HSA-749455] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] - Homo sapiens
consumedByEvent
[Reaction:R-HSA-749456] Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi - Homo sapiens
created
[InstanceEdit:380069] Jassal, Bijay, 2008年11月07日
dbId
380091
displayName
Ligand:GPCR complexes that activate Gi [plasma membrane]
hasMember
[Complex:R-HSA-444688] C3AR1:C3a [plasma membrane] - Homo sapiens
[Complex:R-HSA-389873] AGTR2:AGT(25-32) [plasma membrane] - Homo sapiens
[Complex:R-HSA-374316] APLNR:Apelin peptides [plasma membrane] - Homo sapiens
[Complex:R-HSA-374321] Bradykinin receptor:Bradykinin [plasma membrane] - Homo sapiens
[Complex:R-HSA-375354] C5AR1:C5a [plasma membrane] - Homo sapiens
[Complex:R-HSA-374150] GPER1:ESTG [plasma membrane] - Homo sapiens
[Complex:R-HSA-374779] Neuropeptides B/W receptor:neuropeptides B/W [plasma membrane] - Homo sapiens
[Complex:R-HSA-374725] Nociceptin receptor:Nociceptin [plasma membrane] - Homo sapiens
[Complex:R-HSA-374302] Opioid receptor:opioid ligand [plasma membrane] - Homo sapiens
[Complex:R-HSA-373268] CCR1,2,8:CCL16 [plasma membrane] - Homo sapiens
[Complex:R-HSA-373299] CCR3,4,5:CCL5(24-91) [plasma membrane] - Homo sapiens
[Complex:R-HSA-373236] CCR10:CCL27,28 [plasma membrane] - Homo sapiens
[Complex:R-HSA-373235] CCR6:CCL20 [plasma membrane] - Homo sapiens
[Complex:R-HSA-373319] CCR7:CCL19,21 [plasma membrane] - Homo sapiens
[Complex:R-HSA-373329] CCR9:CCL25 [plasma membrane] - Homo sapiens
[Complex:R-HSA-373801] CXCR1:CXCR1 ligands [plasma membrane] - Homo sapiens
[Complex:R-HSA-373773] CXCR2:CXCR2 ligands [plasma membrane] - Homo sapiens
[Complex:R-HSA-374141] CXCR3:CXCR3 ligands [plasma membrane] - Homo sapiens
[Complex:R-HSA-374203] CXCR4,7:CXCL12 [plasma membrane] - Homo sapiens
[Complex:R-HSA-444551] CXCR5:CXCL13 [plasma membrane] - Homo sapiens
[Complex:R-HSA-373797] CXCR6:CXCL16 [plasma membrane] - Homo sapiens
[Complex:R-HSA-374763] Somatostatin receptor:somatostatin [plasma membrane] - Homo sapiens
[Complex:R-HSA-390955] HTR1B,D,E,F,HTR5A:5HT [plasma membrane] - Homo sapiens
[Complex:R-HSA-390876] HRH4:Hist [plasma membrane] - Homo sapiens
[Complex:R-HSA-390849] DRD3,4:DA [plasma membrane] - Homo sapiens
[Complex:R-HSA-390700] ADRA2A,B,C:ADR,NAd [plasma membrane] - Homo sapiens
[Complex:R-HSA-390685] CHRM2,CHRM4:AcCho [plasma membrane] - Homo sapiens
[Complex:R-HSA-417869] P2RY4:UTP [plasma membrane] - Homo sapiens
[Complex:R-HSA-417834] P2RY12:ADP [plasma membrane] - Homo sapiens
[Complex:R-HSA-417853] P2RY13:ADP [plasma membrane] - Homo sapiens
[Complex:R-HSA-417863] P2RY14:UDP-Glc [plasma membrane] - Homo sapiens
[Complex:R-HSA-418897] ADORA1,3:Ade-Rib [plasma membrane] - Homo sapiens
[Complex:R-HSA-419404] CNRs:Cannabinoids [plasma membrane] - Homo sapiens
[Complex:R-HSA-420743] CASR:Ca2+ [plasma membrane] - Homo sapiens
[Complex:R-HSA-389042] GALR1-3:GAL [plasma membrane] - Homo sapiens
[Complex:R-HSA-416381] GPR17:Cysteinyl leukotrienes [plasma membrane] - Homo sapiens
[Complex:R-HSA-416875] PTGDR2:PGD2 [plasma membrane] - Homo sapiens
[Complex:R-HSA-419353] LPAR1,2,3,5:LPA [plasma membrane] - Homo sapiens
[Complex:R-HSA-419365] Melatonin receptors:melatonin [plasma membrane] - Homo sapiens
[Complex:R-HSA-388866] Neuropeptide Y receptors:NPY receptor ligands [plasma membrane] - Homo sapiens
[Complex:R-HSA-416461] OXER1:5-oxoETE [plasma membrane] - Homo sapiens
[Complex:R-HSA-391924] PTGER3:PGE2 [plasma membrane] - Homo sapiens
[Complex:R-HSA-419346] S1PR2-5:S1P [plasma membrane] - Homo sapiens
[Complex:R-HSA-416459] FPR2:FPR2 ligands [plasma membrane] - Homo sapiens
[Complex:R-HSA-444509] FPR1:FMLP [plasma membrane] - Homo sapiens
[Complex:R-HSA-444553] FPR3:FPR3 ligands [plasma membrane] - Homo sapiens
[Complex:R-HSA-444847] RXFP3:Relaxin-3 [plasma membrane] - Homo sapiens
[Complex:R-HSA-444907] RXFP4:RXFP4 ligands [plasma membrane] - Homo sapiens
[Complex:R-HSA-517528] GPR18:NAGLY [plasma membrane] - Homo sapiens
[Complex:R-HSA-947670] MCHR1,MCHR2:PMCH(147-165) [plasma membrane] - Homo sapiens
[Complex:R-HSA-981831] NMUR2:NMS [plasma membrane] - Homo sapiens
[Complex:R-HSA-964802] NMUR1,NMUR2:NMU [plasma membrane] - Homo sapiens
[Complex:R-HSA-3222582] Group II and III metabotropic gutamate receptors:Glu [plasma membrane] - Homo sapiens
[Complex:R-HSA-3299631] TAS2Rs:Bitter-tasting compounds [plasma membrane] - Homo sapiens
[Complex:R-HSA-3296289] SUCNR1:SUCCA [plasma membrane] - Homo sapiens
[Complex:R-HSA-964778] OXGR1:2OG [plasma membrane] - Homo sapiens
[Complex:R-HSA-3296263] HCAR1:LACT [plasma membrane] - Homo sapiens
[Complex:R-HSA-3296315] HCAR2:HCAR2 ligands [plasma membrane] - Homo sapiens
[Complex:R-HSA-3296296] HCAR3:HCAR3 ligands [plasma membrane] - Homo sapiens
[Complex:R-HSA-373352] CX3CR1:CX3CL1 [plasma membrane] - Homo sapiens
[Complex:R-HSA-8862737] CCL13:CCL2,CCR3 [plasma membrane] - Homo sapiens
[Complex:R-HSA-8851339] CCR8:CCL1 [plasma membrane] - Homo sapiens
[Complex:R-HSA-8865354] CCL4,(CCL4L):CCR5,CCR1 [plasma membrane] - Homo sapiens
[Complex:R-HSA-8851784] GPR183:7alpha,25-dihydroxycholesterol [plasma membrane] - Homo sapiens
[Complex:R-HSA-5336181] GPR37:PSAP fragments [plasma membrane] - Homo sapiens
[Complex:R-HSA-5336185] GPR37L1:Prosaposin fragments [plasma membrane] - Homo sapiens
[Complex:R-HSA-3499321] GPR31:12(S)-HETE [plasma membrane] - Homo sapiens
[Complex:R-HSA-420698] GABBR1:GABBR2:GABA [plasma membrane] - Homo sapiens
[Complex:R-HSA-444655] TAS1R1:TAS1R3:L-Glu [plasma membrane] - Homo sapiens
[Complex:R-HSA-444662] TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] - Homo sapiens
inDisease
false
inferredTo
[DefinedSet:R-MMU-380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - Mus musculus
[DefinedSet:R-RNO-380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - Rattus norvegicus
[DefinedSet:R-CFA-380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - Canis familiaris
[DefinedSet:R-BTA-380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - Bos taurus
[DefinedSet:R-SSC-380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - Sus scrofa
[DefinedSet:R-DRE-380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - Danio rerio
[DefinedSet:R-XTR-380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - Xenopus tropicalis
[DefinedSet:R-GGA-380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - Gallus gallus
[DefinedSet:R-DME-380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - Drosophila melanogaster
[DefinedSet:R-CEL-380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - Caenorhabditis elegans
[Complex:R-DDI-420698] GABBR1:GABBR2:GABA [plasma membrane] - Dictyostelium discoideum
maxDepth
5
modified
[InstanceEdit:9665115] Murillo, Julieth, 2019年10月29日
name
Ligand:GPCR complexes that activate Gi
producedByEvent
[Reaction:R-HSA-749454] The Ligand:GPCR:Gi complex dissociates - Homo sapiens
schemaClass
DefinedSet
species
[Species:48887] Homo sapiens
stId
R-HSA-380091
updateTrackers
[UpdateTracker:9868194] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v29:[addHasMember]
[UpdateTracker:9905174] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v83:[updateContainedMemberOrCandidate]
[UpdateTracker:9883421] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v45:[add_removeHasMember, updateContainedMemberOrCandidate]
[UpdateTracker:9953808] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v93:[updateContainedMemberOrCandidate]
[UpdateTracker:9899031] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v64:[updateContainedMemberOrCandidate]
[UpdateTracker:9898053] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v63:[addHasMember, updateContainedMemberOrCandidate]
[UpdateTracker:9872390] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v41:[updateContainedMemberOrCandidate]
[UpdateTracker:9869189] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v33:[modifyName, updateContainedMemberOrCandidate]
[UpdateTracker:9900698] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v70:[updateContainedMemberOrCandidate]
[UpdateTracker:9872888] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v42:[updateContainedMemberOrCandidate]
[UpdateTracker:9901044] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v72:[updateContainedMemberOrCandidate]
[UpdateTracker:9879109] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v44:[updateContainedMemberOrCandidate]
[UpdateTracker:9868197] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v30:[updateContainedMemberOrCandidate]
[UpdateTracker:9892445] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v53:[updateContainedMemberOrCandidate]
[UpdateTracker:9940044] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v92:[updateContainedMemberOrCandidate]
[UpdateTracker:9893518] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v56:[updateContainedMemberOrCandidate]
[UpdateTracker:9887667] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v46:[updateContainedMemberOrCandidate]
[UpdateTracker:9869912] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v35:[addHasMember]
[UpdateTracker:9899727] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v67:[updateContainedMemberOrCandidate]
[UpdateTracker:9892910] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v54:[updateContainedMemberOrCandidate]
[UpdateTracker:9902273] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v77:[updateContainedMemberOrCandidate]
[UpdateTracker:9867948] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v28:[add_removeHasMember, modifyName]
[UpdateTracker:9901676] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v74:[updateContainedMemberOrCandidate]
[UpdateTracker:9895783] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v59:[updateContainedMemberOrCandidate]
[UpdateTracker:9899439] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v66:[updateContainedMemberOrCandidate]
[UpdateTracker:9869773] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v34:[updateContainedMemberOrCandidate]
[UpdateTracker:9896513] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v60:[updateContainedMemberOrCandidate]
[UpdateTracker:9868477] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v31:[updateContainedMemberOrCandidate]
[UpdateTracker:9868654] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v32:[addHasMember, updateContainedMemberOrCandidate]
Referrals
(hasComponent)
[Complex:R-HSA-749455] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane]
[Complex:R-HSA-749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane]
(input)
[Reaction:R-HSA-749456] Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi
(output)
[Reaction:R-HSA-749454] The Ligand:GPCR:Gi complex dissociates
(updatedInstance)
[UpdateTracker:9868194] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v29:[addHasMember]
[UpdateTracker:9905174] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v83:[updateContainedMemberOrCandidate]
[UpdateTracker:9883421] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v45:[add_removeHasMember, updateContainedMemberOrCandidate]
[UpdateTracker:9953808] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v93:[updateContainedMemberOrCandidate]
[UpdateTracker:9899031] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v64:[updateContainedMemberOrCandidate]
[UpdateTracker:9898053] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v63:[addHasMember, updateContainedMemberOrCandidate]
[UpdateTracker:9872390] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v41:[updateContainedMemberOrCandidate]
[UpdateTracker:9869189] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v33:[modifyName, updateContainedMemberOrCandidate]
[UpdateTracker:9900698] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v70:[updateContainedMemberOrCandidate]
[UpdateTracker:9872888] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v42:[updateContainedMemberOrCandidate]
[UpdateTracker:9901044] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v72:[updateContainedMemberOrCandidate]
[UpdateTracker:9879109] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v44:[updateContainedMemberOrCandidate]
[UpdateTracker:9868197] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v30:[updateContainedMemberOrCandidate]
[UpdateTracker:9892445] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v53:[updateContainedMemberOrCandidate]
[UpdateTracker:9940044] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v92:[updateContainedMemberOrCandidate]
[UpdateTracker:9893518] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v56:[updateContainedMemberOrCandidate]
[UpdateTracker:9887667] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v46:[updateContainedMemberOrCandidate]
[UpdateTracker:9869912] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v35:[addHasMember]
[UpdateTracker:9899727] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v67:[updateContainedMemberOrCandidate]
[UpdateTracker:9892910] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v54:[updateContainedMemberOrCandidate]
[UpdateTracker:9902273] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v77:[updateContainedMemberOrCandidate]
[UpdateTracker:9867948] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v28:[add_removeHasMember, modifyName]
[UpdateTracker:9901676] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v74:[updateContainedMemberOrCandidate]
[UpdateTracker:9895783] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v59:[updateContainedMemberOrCandidate]
[UpdateTracker:9899439] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v66:[updateContainedMemberOrCandidate]
[UpdateTracker:9869773] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v34:[updateContainedMemberOrCandidate]
[UpdateTracker:9896513] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v60:[updateContainedMemberOrCandidate]
[UpdateTracker:9868477] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v31:[updateContainedMemberOrCandidate]
[UpdateTracker:9868654] Update Tracker - [DefinedSet:380091] Ligand:GPCR complexes that activate Gi [plasma membrane] - v32:[addHasMember, updateContainedMemberOrCandidate]
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