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Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 Show undefined attributes

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authored

[InstanceEdit:380069] Jassal, Bijay, 2008年11月07日

catalystActivity

[CatalystActivity:380089] guanyl-nucleotide exchange factor activity of LTC4:CyslTR1,2 [plasma membrane]

category transition

compartment

created [InstanceEdit:379045] Jassal, Bijay, 2008年10月10日

dbId 379048

displayName Liganded Gq/11-activating GPCRs act as GEFs for Gq/11

edited

[InstanceEdit:813668] Jupe, S, 2010年05月26日

eventOf

[Pathway:R-HSA-416476] G alpha (q) signalling events - Homo sapiens

followingEvent

[Reaction:R-HSA-749452] The Ligand:GPCR:Gq complex dissociates - Homo sapiens

input

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:10867632] Weiser, Joel, 2025年08月27日

name

Liganded Gq/11-activating GPCRs act as GEFs for Gq/11

orthologousEvent

output

precedingEvent

[Reaction:R-HSA-749448] Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq - Homo sapiens

releaseDate 2008年12月17日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:387043] D'Eustachio, P, 2008年11月29日 18:33:05

revised

[InstanceEdit:9012014] Varusai, Thawfeek, 2017年07月10日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-379048

summation

[Summation:380079] G alpha q protein (or Gq/11) consists of four family members...

updateTrackers

Referrals

(updatedInstance)

(hasEvent)

[Pathway:R-HSA-416476] G alpha (q) signalling events

(precedingEvent)

[Reaction:R-HSA-749452] The Ligand:GPCR:Gq complex dissociates

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