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Schema
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Pathway
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Entries
Class A/1 (Rhodopsin-like receptors)
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authored
[InstanceEdit:372802] Jassal, B, 2008年07月03日 10:57:39
created
[InstanceEdit:373072] Jassal, Bijay, 2008年07月14日
dbId
373076
diseasePathways
[Pathway:R-HSA-5619099] Defective AVP does not bind AVPR1A,B and causes neurohypophyseal diabetes insipidus (NDI) - Homo sapiens
[Pathway:R-HSA-5579031] Defective ACTH causes obesity and POMCD - Homo sapiens
displayName
Class A/1 (Rhodopsin-like receptors)
edited
[InstanceEdit:375493] D'Eustachio, P, 2008年09月01日 11:58:31
eventOf
[Pathway:R-HSA-500792] GPCR ligand binding - Homo sapiens
goBiologicalProcess
[GO_BiologicalProcess:11091] G protein-coupled receptor signaling pathway
hasDiagram
true
hasEHLD
false
hasEvent
[Pathway:R-HSA-375276] Peptide ligand-binding receptors - Homo sapiens
[Pathway:R-HSA-375280] Amine ligand-binding receptors - Homo sapiens
[Pathway:R-HSA-375281] Hormone ligand-binding receptors - Homo sapiens
[Pathway:R-HSA-391903] Eicosanoid ligand-binding receptors - Homo sapiens
[Pathway:R-HSA-418038] Nucleotide-like (purinergic) receptors - Homo sapiens
[Pathway:R-HSA-3296197] Hydroxycarboxylic acid-binding receptors - Homo sapiens
[Reaction:R-HSA-419426] Cannabinoid receptors can bind cannabinoids - Homo sapiens
[Reaction:R-HSA-9696323] CNRs bind CNR agonists - Homo sapiens
[Reaction:R-HSA-419351] PAF receptor binds platelet activating factor - Homo sapiens
[Reaction:R-HSA-419334] Melatonin receptors can bind melatonin - Homo sapiens
[Pathway:R-HSA-419408] Lysosphingolipid and LPA receptors - Homo sapiens
[Pathway:R-HSA-419771] Opsins - Homo sapiens
[Pathway:R-HSA-444209] Free fatty acid receptors - Homo sapiens
[Reaction:R-HSA-444731] GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors - Homo sapiens
[Reaction:R-HSA-444661] HCAR2 binds HCAR2 ligands - Homo sapiens
[Reaction:R-HSA-444654] G-protein coupled bile acid receptor binds lithocholic acid - Homo sapiens
[Reaction:R-HSA-517536] N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine - Homo sapiens
[Reaction:R-HSA-444572] Zinc is an agonist of GPR39 - Homo sapiens
[Reaction:R-HSA-964773] OXGR1 binds 2OG - Homo sapiens
[Reaction:R-HSA-3296244] SUCNR1 binds SUCCA - Homo sapiens
[Reaction:R-HSA-6805205] GPR35 binds kynurenic acid - Homo sapiens
[Reaction:R-HSA-8851679] GPR183 binds 7alpha,25-dihydroxycholesterol - Homo sapiens
[Reaction:R-HSA-8862700] CMKLR1 binds Resolvin E1 - Homo sapiens
isInDisease
false
isInferred
false
lastUpdatedDate
2022年06月09日
literatureReference
[LiteratureReference:372775] The 7 TM G-protein-coupled receptor target family
maxDepth
4
modified
[InstanceEdit:11033291] Weiser, Joel, 2025年08月28日
name
Class A/1 (Rhodopsin-like receptors)
orthologousEvent
[Pathway:R-RNO-373076] Class A/1 (Rhodopsin-like receptors) - Rattus norvegicus
[Pathway:R-MMU-373076] Class A/1 (Rhodopsin-like receptors) - Mus musculus
[Pathway:R-CFA-373076] Class A/1 (Rhodopsin-like receptors) - Canis familiaris
[Pathway:R-BTA-373076] Class A/1 (Rhodopsin-like receptors) - Bos taurus
[Pathway:R-SSC-373076] Class A/1 (Rhodopsin-like receptors) - Sus scrofa
[Pathway:R-DRE-373076] Class A/1 (Rhodopsin-like receptors) - Danio rerio
[Pathway:R-XTR-373076] Class A/1 (Rhodopsin-like receptors) - Xenopus tropicalis
[Pathway:R-GGA-373076] Class A/1 (Rhodopsin-like receptors) - Gallus gallus
[Pathway:R-DME-373076] Class A/1 (Rhodopsin-like receptors) - Drosophila melanogaster
[Pathway:R-CEL-373076] Class A/1 (Rhodopsin-like receptors) - Caenorhabditis elegans
[Pathway:R-SPO-373076] Class A/1 (Rhodopsin-like receptors) - Schizosaccharomyces pombe
[Pathway:R-SCE-373076] Class A/1 (Rhodopsin-like receptors) - Saccharomyces cerevisiae
[Pathway:R-DDI-373076] Class A/1 (Rhodopsin-like receptors) - Dictyostelium discoideum
releaseDate
2008年09月30日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:375494] Bockaert, J, 2008年09月01日 12:04:13
revised
[InstanceEdit:8948916] D'Eustachio, Peter, 2016年11月17日
schemaClass
Pathway
species
[Species:48887] Homo sapiens
stId
R-HSA-373076
summation
[Summation:373059] Rhodopsin-like receptors (class A/1) are the largest group o...
updateTrackers
[UpdateTracker:9786033] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v50:[updateIndirectRLE]
[UpdateTracker:9783137] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v57:[updateContainedPathway]
[UpdateTracker:9776765] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v74:[updateContainedPathway, updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9791645] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v28:[addHasEvent, updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9774760] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v81:[addHasEvent, updateContainedPathway]
[UpdateTracker:9779155] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v66:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9788621] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v41:[updateContainedPathway]
[UpdateTracker:9790027] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v35:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9790296] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v34:[updateIndirectRLE]
[UpdateTracker:9791011] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v32:[addHasEvent, updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9778698] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v67:[updateContainedPathway]
[UpdateTracker:9787818] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v44:[updateIndirectRLE]
[UpdateTracker:9788327] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v42:[updateContainedPathway]
[UpdateTracker:9791719] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v27:[updateContainedPathway]
[UpdateTracker:9782860] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v58:[updateContainedPathway]
[UpdateTracker:9782091] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v59:[addHasEvent, updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9786663] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v49:[updateContainedPathway]
[UpdateTracker:9790679] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v33:[addHasEvent, updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9791533] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v29:[addHasEvent]
[UpdateTracker:9784352] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v54:[updateContainedPathway]
[UpdateTracker:9787361] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v45:[addHasEvent, updateContainedPathway, updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9791339] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v31:[updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9776262] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v77:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9788173] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v43:[updateContainedPathway]
[UpdateTracker:9777504] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v70:[updateContainedPathway]
[UpdateTracker:9780439] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v63:[updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9781862] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v60:[addHasEvent]
[UpdateTracker:9783651] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v56:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9775651] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v78:[updateContainedPathway, updateIndirectRLE]
Referrals
(hasEvent)
[Pathway:R-HSA-500792] GPCR ligand binding
(hasEncapsulatedEvent)
[Pathway:R-HSA-428157] Sphingolipid metabolism
(normalPathway)
[Pathway:R-HSA-5619099] Defective AVP does not bind AVPR1A,B and causes neurohypophyseal diabetes insipidus (NDI)
[Pathway:R-HSA-5579031] Defective ACTH causes obesity and POMCD
(updatedInstance)
[UpdateTracker:9786033] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v50:[updateIndirectRLE]
[UpdateTracker:9783137] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v57:[updateContainedPathway]
[UpdateTracker:9776765] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v74:[updateContainedPathway, updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9791645] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v28:[addHasEvent, updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9774760] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v81:[addHasEvent, updateContainedPathway]
[UpdateTracker:9779155] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v66:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9788621] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v41:[updateContainedPathway]
[UpdateTracker:9790027] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v35:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9790296] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v34:[updateIndirectRLE]
[UpdateTracker:9791011] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v32:[addHasEvent, updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9778698] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v67:[updateContainedPathway]
[UpdateTracker:9787818] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v44:[updateIndirectRLE]
[UpdateTracker:9788327] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v42:[updateContainedPathway]
[UpdateTracker:9791719] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v27:[updateContainedPathway]
[UpdateTracker:9782860] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v58:[updateContainedPathway]
[UpdateTracker:9782091] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v59:[addHasEvent, updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9786663] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v49:[updateContainedPathway]
[UpdateTracker:9790679] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v33:[addHasEvent, updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9791533] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v29:[addHasEvent]
[UpdateTracker:9784352] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v54:[updateContainedPathway]
[UpdateTracker:9787361] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v45:[addHasEvent, updateContainedPathway, updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9791339] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v31:[updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9776262] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v77:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9788173] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v43:[updateContainedPathway]
[UpdateTracker:9777504] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v70:[updateContainedPathway]
[UpdateTracker:9780439] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v63:[updateContainedRLE, updateIndirectRLE]
[UpdateTracker:9781862] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v60:[addHasEvent]
[UpdateTracker:9783651] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v56:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9775651] Update Tracker - [Pathway:373076] Class A/1 (Rhodopsin-like receptors) - v78:[updateContainedPathway, updateIndirectRLE]
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