Reactome Pathway Database

Schema > Reaction > Entries

Recruitment of GRB2 to p-PTK2 Show undefined attributes

authored

[InstanceEdit:354193] Garapati, P V, 2008年06月16日 17:13:06

category binding

compartment

created [InstanceEdit:354078] Garapati, P V, 2008年06月16日 17:02:05

dbId 354087

displayName Recruitment of GRB2 to p-PTK2

edited

[InstanceEdit:354193] Garapati, P V, 2008年06月16日 17:13:06

eventOf

[Pathway:R-HSA-354194] GRB2:SOS provides linkage to MAPK signaling for Integrins - Homo sapiens

followingEvent

[Reaction:R-HSA-354165] Interaction of SOS with GRB2 bound to FADK1 - Homo sapiens

input

isInDisease false

isInferred false

literatureReference

maxDepth 1

modified [InstanceEdit:10867632] Weiser, Joel, 2025年08月27日

name

Recruitment of GRB2 to p-PTK2

orthologousEvent

output

[Complex:R-HSA-354113] GRB2 bound to pPTK2 in Focal adhesion [plasma membrane]

precedingEvent

[Reaction:R-HSA-354124] Phosphorylation of pPTK2 by SRC - Homo sapiens

releaseDate 2008年12月17日

requiredInputComponent

[EntityWithAccessionedSequence:R-HSA-354128] p-6Y-PTK2 [cytosol] - Homo sapiens

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:377695] Shattil, SJ, 2008年09月16日 06:21:39

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-354087

summation

[Summation:372629] Phosphorylated tyrosine 925 in the FAT domain of PTK2/FAK cr...

updateTrackers

Referrals

(updatedInstance)

(hasEvent)

[Pathway:R-HSA-354194] GRB2:SOS provides linkage to MAPK signaling for Integrins

(precedingEvent)

[Reaction:R-HSA-354165] Interaction of SOS with GRB2 bound to FADK1

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