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Schema
>
BlackBoxEvent
>
Entries
26S proteosome degrades ODC holoenzyme complex
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authored
[InstanceEdit:350583] Gopinathrao, G, 2008年05月19日 18:50:15
catalystActivity
[CatalystActivity:68824] endopeptidase activity of 26S proteasome [cytosol]
category
omitted
compartment
[Compartment:70101] cytosol
dbId
353125
displayName
26S proteosome degrades ODC holoenzyme complex
eventOf
[Pathway:R-HSA-350562] Regulation of ornithine decarboxylase (ODC) - Homo sapiens
followingEvent
[Reaction:R-HSA-350567] Antizyme OAZ binds to Ornithine decarboxylase - Homo sapiens
goBiologicalProcess
[GO_BiologicalProcess:260545] proteasomal ubiquitin-independent protein catabolic process
input
[Complex:R-HSA-353118] ODC:OAZ complex [cytosol]
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:9955805] Structural basis of Ornithine Decarboxylase inactivation and accelerated degradation by polyamine sensor Antizyme1
[LiteratureReference:350585] Determinants of proteasome recognition of ornithine decarboxylase, a ubiquitin-independent substrate
maxDepth
1
modified
[InstanceEdit:11001822] Weiser, Joel, 2025年08月28日
name
26S proteosome degrades ODC holoenzyme complex
orthologousEvent
[BlackBoxEvent:R-SPO-353125] 26S proteosome degrades ODC holoenzyme complex - Schizosaccharomyces pombe
[BlackBoxEvent:R-CEL-353125] 26S proteosome degrades ODC holoenzyme complex - Caenorhabditis elegans
[BlackBoxEvent:R-DME-353125] 26S proteosome degrades ODC holoenzyme complex - Drosophila melanogaster
[BlackBoxEvent:R-GGA-353125] 26S proteosome degrades ODC holoenzyme complex - Gallus gallus
[BlackBoxEvent:R-XTR-353125] 26S proteosome degrades ODC holoenzyme complex - Xenopus tropicalis
[BlackBoxEvent:R-DRE-353125] 26S proteosome degrades ODC holoenzyme complex - Danio rerio
[BlackBoxEvent:R-SSC-353125] 26S proteosome degrades ODC holoenzyme complex - Sus scrofa
[BlackBoxEvent:R-BTA-353125] 26S proteosome degrades ODC holoenzyme complex - Bos taurus
[BlackBoxEvent:R-CFA-353125] 26S proteosome degrades ODC holoenzyme complex - Canis familiaris
[BlackBoxEvent:R-RNO-353125] 26S proteosome degrades ODC holoenzyme complex - Rattus norvegicus
[BlackBoxEvent:R-MMU-353125] 26S proteosome degrades ODC holoenzyme complex - Mus musculus
output
[DefinedSet:R-HSA-350592] OAZ [cytosol]
precedingEvent
[Reaction:R-HSA-350567] Antizyme OAZ binds to Ornithine decarboxylase - Homo sapiens
releaseDate
2008年06月30日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:354206] D'Eustachio, P, 2008年06月12日 17:57:32
schemaClass
BlackBoxEvent
species
[Species:48887] Homo sapiens
stId
R-HSA-353125
summation
[Summation:353119] The rapid turnover of ODC is brought about by the 26S protea...
updateTrackers
[UpdateTracker:9964660] Update Tracker - [BlackBoxEvent:353125] 26S proteosome degrades ODC holoenzyme complex - v94:[modifyText, removeLiteratureReference]
[UpdateTracker:9965337] Update Tracker - [BlackBoxEvent:353125] 26S proteosome degrades ODC holoenzyme complex - v94:[modifyText, removeLiteratureReference]
Referrals
(updatedInstance)
[UpdateTracker:9964660] Update Tracker - [BlackBoxEvent:353125] 26S proteosome degrades ODC holoenzyme complex - v94:[modifyText, removeLiteratureReference]
[UpdateTracker:9965337] Update Tracker - [BlackBoxEvent:353125] 26S proteosome degrades ODC holoenzyme complex - v94:[modifyText, removeLiteratureReference]
(hasEvent)
[Pathway:R-HSA-350562] Regulation of ornithine decarboxylase (ODC)
(precedingEvent)
[Reaction:R-HSA-350567] Antizyme OAZ binds to Ornithine decarboxylase
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