Reactome Pathway Database

Schema > EntityWithAccessionedSequence > Entries

SMAD4 R361C [cytosol] Show undefined attributes

compartment

[Compartment:70101] cytosol

created [InstanceEdit:3310990] Orlic-Milacic, M, 2013年04月24日

crossReference

dbId 3310983

disease

displayName SMAD4 R361C [cytosol]

endCoordinate 552

hasModifiedResidue

[ReplacedResidue:3310989] L-arginine 361 replaced with L-cysteine

inDisease true

literatureReference

[LiteratureReference:3318202] A structural basis for mutational inactivation of the tumour suppressor Smad4
[LiteratureReference:3304374] SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer

maxDepth 1

memberOf

[CandidateSet:R-HSA-3311017] SMAD4 MH2 domain mutants [cytosol] - Homo sapiens

modified [InstanceEdit:3318205] Orlic-Milacic, M, 2013年04月25日

name

SMAD4 R361C
SMAD4 Arg361Cys

referenceEntity [ReferenceGeneProduct:uniprot:Q13485] UniProt:Q13485 SMAD4

referenceType ReferenceGeneProduct

schemaClass EntityWithAccessionedSequence

species [Species:48887] Homo sapiens

stId R-HSA-3310983

startCoordinate 1

Referrals

(hasMember)

[CandidateSet:R-HSA-3311017] SMAD4 MH2 domain mutants [cytosol]

© 2025 Reactome

Cite Us!