Reactome Pathway Database

Schema > Complex > Entries

POU5F1:SOX2:NANOG:GSC gene [nucleoplasm] Show undefined attributes

compartment

[Compartment:7660] nucleoplasm

created [InstanceEdit:2888999] May, B, 2012年12月31日

dbId 2889033

displayName POU5F1:SOX2:NANOG:GSC gene [nucleoplasm]

hasComponent

inDisease false

isChimeric false

literatureReference

[LiteratureReference:452538] Core transcriptional regulatory circuitry in human embryonic stem cells
[LiteratureReference:5246719] Human DNA methylomes at base resolution show widespread epigenomic differences
[LiteratureReference:5250252] Transposable elements have rewired the core regulatory network of human embryonic stem cells

maxDepth 2

modified [InstanceEdit:5250254] May, B, 2014年01月24日

name

POU5F1:SOX2:NANOG:GSC gene
OCT4:SOX2:NANOG:GSC gene

negativelyRegulates

[NegativeGeneExpressionRegulation:5163256] Negative gene expression regulation by 'POU5F1:SOX2:NANOG:GSC gene [nucleoplasm]'

producedByEvent

[Reaction:R-HSA-2972948] POU5F1 (OCT4), SOX2, NANOG bind the GSC promoter - Homo sapiens

schemaClass Complex

species

[Species:48887] Homo sapiens

stId R-HSA-2889033

Referrals

(output)

[Reaction:R-HSA-2972948] POU5F1 (OCT4), SOX2, NANOG bind the GSC promoter

(regulator)

[NegativeGeneExpressionRegulation:5163256] Negative gene expression regulation by 'POU5F1:SOX2:NANOG:GSC gene [nucleoplasm]'

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