Reactome Pathway Database

Schema > EntityWithAccessionedSequence > Entries

PIK3R1 D560Y [plasma membrane] Show undefined attributes

compartment

[Compartment:876] plasma membrane

created [InstanceEdit:2399428] Orlic-Milacic, M, 2012年07月09日

crossReference

dbId 2399421

disease

displayName PIK3R1 D560Y [plasma membrane]

endCoordinate 724

hasModifiedResidue

[ReplacedResidue:2399429] L-aspartic acid 560 replaced with L-tyrosine

inDisease true

literatureReference

[LiteratureReference:2399688] Somatic mutations in p85alpha promote tumorigenesis through class IA PI3K activation

maxDepth 1

memberOf

[CandidateSet:R-HSA-2399665] PIK3R1 iSH2 domain mutants [plasma membrane] - Homo sapiens

modified [InstanceEdit:5624358] Jupe, Steve, 2014年09月26日

name

PIK3R1 D560Y
PIK3R1 Asp560Tyr

referenceEntity [ReferenceGeneProduct:uniprot:P27986] UniProt:P27986 PIK3R1

referenceType ReferenceGeneProduct

schemaClass EntityWithAccessionedSequence

species [Species:48887] Homo sapiens

stId R-HSA-2399421

startCoordinate 1

summation

[Summation:2399704] The substitution of aspartic acid residue with tyrosine at p...

updateTrackers

[UpdateTracker:9888023] Update Tracker - [EntityWithAccessionedSequence:2399421] PIK3R1 D560Y [plasma membrane] - v46:[modifyName]

Referrals

(updatedInstance)

[UpdateTracker:9888023] Update Tracker - [EntityWithAccessionedSequence:2399421] PIK3R1 D560Y [plasma membrane] - v46:[modifyName]

(hasMember)

[CandidateSet:R-HSA-2399665] PIK3R1 iSH2 domain mutants [plasma membrane]

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