Reactome Pathway Database

Schema > EntityWithAccessionedSequence > Entries

PTEN S170N [cytosol] Show undefined attributes

compartment

[Compartment:70101] cytosol

created [InstanceEdit:2318411] Orlic-Milacic, M, 2012年06月13日

crossReference

dbId 2318408

disease

displayName PTEN S170N [cytosol]

endCoordinate 403

hasModifiedResidue

[ReplacedResidue:2318409] L-serine 170 replaced with L-asparagine

inDisease true

literatureReference

[LiteratureReference:1889775] Functional evaluation of PTEN missense mutations using in vitro phosphoinositide phosphatase assay
[LiteratureReference:2317505] Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association

maxDepth 1

memberOf

[CandidateSet:R-HSA-2317372] PTEN Phosphatase Domain Missense Mutants [cytosol] - Homo sapiens

modified [InstanceEdit:3662293] Orlic-Milacic, M, 2013年06月06日

name

PTEN S170N
PTEN Ser170Asn

referenceEntity [ReferenceGeneProduct:uniprot:P60484] UniProt:P60484 PTEN

referenceType ReferenceGeneProduct

schemaClass EntityWithAccessionedSequence

species [Species:48887] Homo sapiens

stId R-HSA-2318408

startCoordinate 1

summation

[Summation:2318412] PTEN missense mutation that results in the substitution of s...

updateTrackers

[UpdateTracker:9887934] Update Tracker - [EntityWithAccessionedSequence:2318408] PTEN S170N [cytosol] - v46:[modifyName]

Referrals

(updatedInstance)

[UpdateTracker:9887934] Update Tracker - [EntityWithAccessionedSequence:2318408] PTEN S170N [cytosol] - v46:[modifyName]

(hasMember)

[CandidateSet:R-HSA-2317372] PTEN Phosphatase Domain Missense Mutants [cytosol]

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