Reactome Pathway Database

Schema > Reaction > Entries

Fibrillin C-terminal processing Show undefined attributes

authored

[InstanceEdit:2214334] Jupe, S, 2012年04月30日

catalystActivity

[CatalystActivity:2159870] serine-type endopeptidase activity of FURIN [plasma membrane]

category transition

compartment

[Compartment:876] plasma membrane

created [InstanceEdit:2129374] Jupe, S, 2012年02月21日

dbId 2129357

displayName Fibrillin C-terminal processing

edited

[InstanceEdit:2580335] Jupe, S, 2012年11月12日

eventOf

[Pathway:R-HSA-1566948] Elastic fibre formation - Homo sapiens

followingEvent

[Polymerisation:R-HSA-2129362] Fibrillin microfibril assembly - Homo sapiens

input

[CandidateSet:R-HSA-2159860] Profibrillins [extracellular region]

isChimeric false

isInDisease false

isInferred false

literatureReference

[LiteratureReference:2129364] Carboxy-terminal conversion of profibrillin to fibrillin at a basic site by PACE/furin-like activity required for incorporation in the matrix

maxDepth 1

modified [InstanceEdit:10680101] Weiser, Joel, 2025年08月27日

name

Fibrillin C-terminal processing

orthologousEvent

output

releaseDate 2012年12月04日

reviewStatus [ReviewStatus:9821382] five stars

reviewed

[InstanceEdit:2550420] Muiznieks, Lisa, 2012年11月02日

schemaClass Reaction

species

[Species:48887] Homo sapiens

stId R-HSA-2129357

summation

[Summation:2129382] Extracellular deposition of fibrillin requires removal of th...

Referrals

(hasEvent)

[Pathway:R-HSA-1566948] Elastic fibre formation

(precedingEvent)

[Polymerisation:R-HSA-2129362] Fibrillin microfibril assembly

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