Reactome Pathway Database

Schema > CandidateSet > Entries

p-T,p-S-AKT [nucleoplasm] Show undefined attributes

catalystActivities

[CatalystActivity:199274] protein serine/threonine kinase activity of p-T,p-S-AKT [nucleoplasm]

compartment

[Compartment:7660] nucleoplasm

created [InstanceEdit:202071] Jassal, B, 2007年10月18日 12:38:34

dbId 202072

displayName p-T,p-S-AKT [nucleoplasm]

hasCandidate

hasMember

[EntityWithAccessionedSequence:R-HSA-198357] p-T308,S473-AKT1 [nucleoplasm] - Homo sapiens

inDisease false

inferredTo

maxDepth 2

modified [InstanceEdit:9622731] Orlic-Milacic, Marija, 2018年10月01日

name

p-T,p-S-AKT
Active AKT
p-T308,S473-AKT1,(p-T309,S474-AKT2,p-T305,S472-AKT3)

negativelyRegulates

[NegativeRegulation:R-HSA-6805635] Negative regulation by 'p-T, p-S-AKT [nucleoplasm]'

producedByEvent

[Reaction:R-HSA-198298] AKT translocates to the nucleus - Homo sapiens

schemaClass CandidateSet

species

[Species:48887] Homo sapiens

stId R-HSA-202072

updateTrackers

Referrals

(updatedInstance)

(normalEntity)

[EntityFunctionalStatus:2400003] gain_of_function of p-T308,S473-AKT1 E17K [nucleoplasm]

(regulator)

[NegativeRegulation:R-HSA-6805635] Negative regulation by 'p-T, p-S-AKT [nucleoplasm]'

(output)

[Reaction:R-HSA-198298] AKT translocates to the nucleus

(physicalEntity)

[CatalystActivity:199274] protein serine/threonine kinase activity of p-T,p-S-AKT [nucleoplasm]

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