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Entries
DHCA is conjugated with Coenzyme A (SLC27A2 VLCS)
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authored
[InstanceEdit:191331] Jassal, Bijay, 2007年01月19日
catalystActivity
[CatalystActivity:193506] long-chain fatty acid-CoA ligase activity of SLC27A2 [endoplasmic reticulum membrane]
category
transition
compartment
[Compartment:70101] cytosol
[Compartment:12045] endoplasmic reticulum membrane
created
[InstanceEdit:193476] D'Eustachio, P, 2007年02月19日 17:36:33
dbId
193424
displayName
DHCA is conjugated with Coenzyme A (SLC27A2 VLCS)
edited
[InstanceEdit:193475] D'Eustachio, P, 2007年02月17日 19:40:28
eventOf
[Pathway:R-HSA-193368] Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol - Homo sapiens
followingEvent
[BlackBoxEvent:R-HSA-193482] 25(R) DHCA-CoA is translocated from the cytosol to the peroxisome - Homo sapiens
input
[SimpleEntity:R-ALL-113592] ATP [cytosol]
[SimpleEntity:R-ALL-76194] CoA-SH [cytosol]
[SimpleEntity:R-ALL-193505] DHCA [cytosol]
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:192044] Human liver-specific very-long-chain acyl-coenzyme A synthetase: cDNA cloning and characterization of a second enzymatically active protein
[LiteratureReference:191995] The human liver-specific homolog of very long-chain acyl-CoA synthetase is cholate:CoA ligase
[LiteratureReference:193432] Participation of two members of the very long-chain acyl-CoA synthetase family in bile acid synthesis and recycling
maxDepth
1
modified
[InstanceEdit:11033291] Weiser, Joel, 2025年08月28日
name
DHCA is conjugated with Coenzyme A (SLC27A2 VLCS)
DHCA + ATP + CoASH => 25(R) DHCA-CoA + AMP + pyrophosphate (SLC27A2 "VLCS")
orthologousEvent
[Reaction:R-SCE-193424] DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) - Saccharomyces cerevisiae
[Reaction:R-CEL-193424] DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) - Caenorhabditis elegans
[Reaction:R-DME-193424] DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) - Drosophila melanogaster
[Reaction:R-GGA-193424] DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) - Gallus gallus
[Reaction:R-XTR-193424] DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) - Xenopus tropicalis
[Reaction:R-SSC-193424] DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) - Sus scrofa
[Reaction:R-BTA-193424] DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) - Bos taurus
[Reaction:R-CFA-193424] DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) - Canis familiaris
[Reaction:R-RNO-193424] DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) - Rattus norvegicus
[Reaction:R-MMU-193424] DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) - Mus musculus
output
[SimpleEntity:R-ALL-193457] 25(R) DHCA-CoA [cytosol]
[SimpleEntity:R-ALL-76577] AMP [cytosol]
[SimpleEntity:R-ALL-111294] PPi [cytosol]
precedingEvent
[BlackBoxEvent:R-HSA-193519] DHCA is translocated from the mitochondrial matrix to the cytosol - Homo sapiens
releaseDate
2007年05月15日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:197117] D'Eustachio, P, 2007年04月30日 14:43:26
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-193424
summation
[Summation:193438] DHCA (25(R) 3alpha,7alpha-dihydroxy-5beta-cholestanoate), co...
updateTrackers
[UpdateTracker:9790614] Update Tracker - [Reaction:193424] DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) - v33:[modifyText, removeOutput]
Referrals
(updatedInstance)
[UpdateTracker:9790614] Update Tracker - [Reaction:193424] DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) - v33:[modifyText, removeOutput]
(hasEvent)
[Pathway:R-HSA-193368] Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
(precedingEvent)
[BlackBoxEvent:R-HSA-193482] 25(R) DHCA-CoA is translocated from the cytosol to the peroxisome
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