CYP8B1 12-hydroxylates 4CHOL7aOLONE

authored
catalystActivity
category transition
compartment
created [InstanceEdit:191989] Jassal, Bijay, 2007年01月26日
crossReference
dbId 192157
displayName CYP8B1 12-hydroxylates 4CHOL7aOLONE
edited
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isInDisease false
isInferred false
literatureReference
maxDepth 1
modified [InstanceEdit:10603480] Weiser, Joel, 2025年08月27日
name
  • CYP8B1 12-hydroxylates 4CHOL7aOLONE
  • 7alpha-hydroxycholest-4-en-3-one + O2 + reduced (NADPH--hemoprotein reductase) => 7alpha,12alpha-dihydroxycholest-4-en-3-one + H(+) + H2O + oxidized (NADPH--hemoprotein reductase)
  • 4-Cholesten-7alpha-ol-3-one is 12alpha-hydroxylated to 7-alpha,12-alpha-dihydroxycholest-4-en-3-one
  • 7-alpha-hydroxycholest-4-en-3-one + NADPH + H+ + O2 => 7-alpha,12-alpha-dihydroxycholest-4-en-3-one + NADP+ + H2O
orthologousEvent
output
precedingEvent
releaseDate 2007年05月15日
reviewStatus [ReviewStatus:9821382] five stars
reviewed
revised
schemaClass Reaction
species
stId R-HSA-192157
summation
updateTrackers
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