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Schema
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Reaction
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Entries
5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol
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authored
[InstanceEdit:191331] Jassal, Bijay, 2007年01月19日
catalystActivity
[CatalystActivity:192098] alcohol dehydrogenase (NADP+) activity of Aldo-keto reductase family [cytosol]
category
transition
compartment
[Compartment:70101] cytosol
created
[InstanceEdit:191989] Jassal, Bijay, 2007年01月26日
dbId
192036
displayName
5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol
edited
[InstanceEdit:193475] D'Eustachio, P, 2007年02月17日 19:40:28
eventOf
[Pathway:R-HSA-193368] Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol - Homo sapiens
followingEvent
[Reaction:R-HSA-192010] 5beta-cholestan-3alpha, 7alpha, 12alpha-triol is translocated from the cytosol to the mitochondrial matrix - Homo sapiens
input
[SimpleEntity:R-ALL-192064] 5beta-cholesten-7alpha, 12alpha-diol-3-one [cytosol]
[SimpleEntity:R-ALL-70106] H+ [cytosol]
[SimpleEntity:R-ALL-29364] NADPH [cytosol]
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:192140] Human types 1 and 3 3 alpha-hydroxysteroid dehydrogenases: differential lability and tissue distribution
maxDepth
1
modified
[InstanceEdit:11033291] Weiser, Joel, 2025年08月28日
name
5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol
5Beta-cholesten-7alpha, 12alpha-diol-3-one + NADPH + H+ => 5beta-cholestan-3alpha, 7alpha, 12alpha-triol + NAPDP+
orthologousEvent
[Reaction:R-SCE-192036] 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol - Saccharomyces cerevisiae
[Reaction:R-SPO-192036] 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol - Schizosaccharomyces pombe
[Reaction:R-DDI-192036] 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol - Dictyostelium discoideum
[Reaction:R-CEL-192036] 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol - Caenorhabditis elegans
[Reaction:R-DME-192036] 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol - Drosophila melanogaster
[Reaction:R-XTR-192036] 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol - Xenopus tropicalis
[Reaction:R-SSC-192036] 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol - Sus scrofa
[Reaction:R-BTA-192036] 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol - Bos taurus
[Reaction:R-RNO-192036] 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol - Rattus norvegicus
[Reaction:R-MMU-192036] 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol - Mus musculus
output
[SimpleEntity:R-ALL-192087] 5beta-cholestan-3alpha,7alpha,12alpha-triol [cytosol]
[SimpleEntity:R-ALL-29366] NADP+ [cytosol]
precedingEvent
[Reaction:R-HSA-192067] 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one - Homo sapiens
releaseDate
2007年05月15日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:197117] D'Eustachio, P, 2007年04月30日 14:43:26
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-192036
summation
[Summation:193826] 5Beta-cholesten-7alpha,12alpha-diol-3-one and NADPH + H+ for...
Referrals
(hasEvent)
[Pathway:R-HSA-193368] Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
(precedingEvent)
[Reaction:R-HSA-192010] 5beta-cholestan-3alpha, 7alpha, 12alpha-triol is translocated from the cytosol to the mitochondrial matrix
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