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Schema
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Reaction
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Entries
Dimerized phospho-IRF3/IRF7 is transported to the nucleus
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authored
[InstanceEdit:450323] Shamovsky, V, 2009年12月16日
category
transition
compartment
[Compartment:70101] cytosol
[Compartment:13231] nuclear envelope
[Compartment:7660] nucleoplasm
created
[InstanceEdit:177664] Gillespie, ME, 2006年04月03日 21:05:10
dbId
177671
displayName
Dimerized phospho-IRF3/IRF7 is transported to the nucleus
edited
[InstanceEdit:1485578] Shamovsky, V, 2011年08月12日
eventOf
[Pathway:R-HSA-9013973] TICAM1-dependent activation of IRF3/IRF7 - Homo sapiens
input
[DefinedSet:R-HSA-450256] phosphorylated IRF3 and/or IRF7 dimer [cytosol]
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:166859] IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway
maxDepth
1
modified
[InstanceEdit:10680101] Weiser, Joel, 2025年08月27日
name
Dimerized phospho-IRF3/IRF7 is transported to the nucleus
orthologousEvent
[Reaction:R-GGA-433967] Dimerized Phospho-IRF3 is Transported To The Nucleus - Gallus gallus
[Reaction:R-GGA-177671] Dimerized phospho-IRF3/IRF7 is transported to the nucleus - Gallus gallus
[Reaction:R-XTR-177671] Dimerized phospho-IRF3/IRF7 is transported to the nucleus - Xenopus tropicalis
[Reaction:R-SSC-177671] Dimerized phospho-IRF3/IRF7 is transported to the nucleus - Sus scrofa
[Reaction:R-BTA-177671] Dimerized phospho-IRF3/IRF7 is transported to the nucleus - Bos taurus
[Reaction:R-CFA-177671] Dimerized phospho-IRF3/IRF7 is transported to the nucleus - Canis familiaris
[Reaction:R-RNO-177671] Dimerized phospho-IRF3/IRF7 is transported to the nucleus - Rattus norvegicus
[Reaction:R-MMU-177671] Dimerized phospho-IRF3/IRF7 is transported to the nucleus - Mus musculus
output
[DefinedSet:R-HSA-450349] phosphorylated IRF3 and/or IRF7 dimer [nucleoplasm]
precedingEvent
[Reaction:R-HSA-168933] Dimerization of phosphorylated IRF3/IRF7 - Homo sapiens
releaseDate
2010年12月14日
requiredInputComponent
[Complex:R-HSA-157689] Nuclear Pore Complex (NPC) [nuclear envelope] - Homo sapiens
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:188961] Gay, NJ, 2006年04月24日 16:48:17
[InstanceEdit:1095192] Gillespie, ME, 2010年11月30日
[InstanceEdit:2582977] Fitzgerald, Katherine A, 2012年11月13日
revised
[InstanceEdit:442879] Shamovsky, V, 2009年09月29日
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-177671
summation
[Summation:178674] IRF3-P:IRF3-P' is translocated from cytosol to nucleoplasm.
updateTrackers
[UpdateTracker:9790940] Update Tracker - [Reaction:177671] Dimerized phospho-IRF3/IRF7 is transported to the nucleus - v32:[add_removeInput, add_removeOutput]
[UpdateTracker:9790049] Update Tracker - [Reaction:177671] Dimerized phospho-IRF3/IRF7 is transported to the nucleus - v35:[modifyText]
Referrals
(updatedInstance)
[UpdateTracker:9790940] Update Tracker - [Reaction:177671] Dimerized phospho-IRF3/IRF7 is transported to the nucleus - v32:[add_removeInput, add_removeOutput]
[UpdateTracker:9790049] Update Tracker - [Reaction:177671] Dimerized phospho-IRF3/IRF7 is transported to the nucleus - v35:[modifyText]
(hasEvent)
[Pathway:R-HSA-9013973] TICAM1-dependent activation of IRF3/IRF7
[Pathway:R-HSA-936964] Activation of IRF3, IRF7 mediated by TBK1, IKK? (IKBKE)
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