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APC/C-mediated degradation of cell cycle proteins
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authored
[InstanceEdit:174241] Lorca, T, Castro, A, 2006年01月26日 00:00:00
created
[InstanceEdit:174149] Matthews, L, 2006年02月17日 00:41:48
dbId
174143
displayName
APC/C-mediated degradation of cell cycle proteins
doi
10.3180/REACT_6828.1
edited
[InstanceEdit:174183] Matthews, L, 2006年01月30日 00:00:00
eventOf
[Pathway:R-HSA-453276] Regulation of mitotic cell cycle - Homo sapiens
figure
[Figure:177045] /figures/Regulation_APC_activators.jpg
goBiologicalProcess
[GO_BiologicalProcess:161960] anaphase-promoting complex-dependent catabolic process
hasDiagram
false
hasEHLD
false
hasEvent
[Pathway:R-HSA-176408] Regulation of APC/C activators between G1/S and early anaphase - Homo sapiens
[Pathway:R-HSA-176814] Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins - Homo sapiens
[Pathway:R-HSA-176407] Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase - Homo sapiens
[Pathway:R-HSA-174178] APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 - Homo sapiens
[Pathway:R-HSA-174084] Autodegradation of Cdh1 by Cdh1:APC/C - Homo sapiens
isInDisease
false
isInferred
false
lastUpdatedDate
2020年06月17日
literatureReference
[LiteratureReference:174118] The anaphase-promoting complex: a key factor in the regulation of cell cycle
[LiteratureReference:174165] The anaphase-promoting complex: proteolysis in mitosis and beyond
maxDepth
6
modified
[InstanceEdit:11033291] Weiser, Joel, 2025年08月28日
name
APC/C-mediated degradation of cell cycle proteins
orthologousEvent
[Pathway:R-SCE-174143] APC/C-mediated degradation of cell cycle proteins - Saccharomyces cerevisiae
[Pathway:R-SPO-174143] APC/C-mediated degradation of cell cycle proteins - Schizosaccharomyces pombe
[Pathway:R-DDI-174143] APC/C-mediated degradation of cell cycle proteins - Dictyostelium discoideum
[Pathway:R-CEL-174143] APC/C-mediated degradation of cell cycle proteins - Caenorhabditis elegans
[Pathway:R-DME-174143] APC/C-mediated degradation of cell cycle proteins - Drosophila melanogaster
[Pathway:R-GGA-174143] APC/C-mediated degradation of cell cycle proteins - Gallus gallus
[Pathway:R-XTR-174143] APC/C-mediated degradation of cell cycle proteins - Xenopus tropicalis
[Pathway:R-DRE-174143] APC/C-mediated degradation of cell cycle proteins - Danio rerio
[Pathway:R-SSC-174143] APC/C-mediated degradation of cell cycle proteins - Sus scrofa
[Pathway:R-BTA-174143] APC/C-mediated degradation of cell cycle proteins - Bos taurus
[Pathway:R-CFA-174143] APC/C-mediated degradation of cell cycle proteins - Canis familiaris
[Pathway:R-RNO-174143] APC/C-mediated degradation of cell cycle proteins - Rattus norvegicus
[Pathway:R-MMU-174143] APC/C-mediated degradation of cell cycle proteins - Mus musculus
releaseDate
2006年04月24日
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:177300] Peters, JM, 2006年03月27日 22:55:09
schemaClass
Pathway
species
[Species:48887] Homo sapiens
stId
R-HSA-174143
summation
[Summation:176413] The Anaphase Promoting Complex or Cyclosome (APC/C) function...
updateTrackers
[UpdateTracker:9782418] Update Tracker - [Pathway:174143] APC/C-mediated degradation of cell cycle proteins - v59:[updateContainedPathway]
[UpdateTracker:9777022] Update Tracker - [Pathway:174143] APC/C-mediated degradation of cell cycle proteins - v73:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9790951] Update Tracker - [Pathway:174143] APC/C-mediated degradation of cell cycle proteins - v32:[updateContainedPathway]
[UpdateTracker:9789669] Update Tracker - [Pathway:174143] APC/C-mediated degradation of cell cycle proteins - v37:[updateContainedPathway]
[UpdateTracker:9789526] Update Tracker - [Pathway:174143] APC/C-mediated degradation of cell cycle proteins - v38:[updateContainedPathway]
[UpdateTracker:9781013] Update Tracker - [Pathway:174143] APC/C-mediated degradation of cell cycle proteins - v61:[updateIndirectRLE]
[UpdateTracker:9786678] Update Tracker - [Pathway:174143] APC/C-mediated degradation of cell cycle proteins - v49:[updateContainedPathway]
[UpdateTracker:9790717] Update Tracker - [Pathway:174143] APC/C-mediated degradation of cell cycle proteins - v33:[updateContainedPathway]
[UpdateTracker:9785828] Update Tracker - [Pathway:174143] APC/C-mediated degradation of cell cycle proteins - v51:[updateContainedPathway]
Referrals
(updatedInstance)
[UpdateTracker:9782418] Update Tracker - [Pathway:174143] APC/C-mediated degradation of cell cycle proteins - v59:[updateContainedPathway]
[UpdateTracker:9777022] Update Tracker - [Pathway:174143] APC/C-mediated degradation of cell cycle proteins - v73:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9790951] Update Tracker - [Pathway:174143] APC/C-mediated degradation of cell cycle proteins - v32:[updateContainedPathway]
[UpdateTracker:9789669] Update Tracker - [Pathway:174143] APC/C-mediated degradation of cell cycle proteins - v37:[updateContainedPathway]
[UpdateTracker:9789526] Update Tracker - [Pathway:174143] APC/C-mediated degradation of cell cycle proteins - v38:[updateContainedPathway]
[UpdateTracker:9781013] Update Tracker - [Pathway:174143] APC/C-mediated degradation of cell cycle proteins - v61:[updateIndirectRLE]
[UpdateTracker:9786678] Update Tracker - [Pathway:174143] APC/C-mediated degradation of cell cycle proteins - v49:[updateContainedPathway]
[UpdateTracker:9790717] Update Tracker - [Pathway:174143] APC/C-mediated degradation of cell cycle proteins - v33:[updateContainedPathway]
[UpdateTracker:9785828] Update Tracker - [Pathway:174143] APC/C-mediated degradation of cell cycle proteins - v51:[updateContainedPathway]
(hasEvent)
[Pathway:R-HSA-453276] Regulation of mitotic cell cycle
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